Comparison of quantitative measurement of foveal avascular zone and macular vessel density in eyes of children with amblyopia and healthy controls: an optical coherence tomography angiography study

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Ihsan YilmazMuhittin Taskapili

Abstract

To quantify vessel density of superficial capillary plexus (SCP), deep capillary plexus (DCP), and the foveal avascular zone (FAZ) of children's amblyopic eyes and to compare the measurements with those of companion eyes and age-matched controls. Fifteen patients with strabismic amblyopia, and 15 age-matched controls were included in this cross-sectional study. SCP, DCP, and FAZ were measured via optical coherence tomographic angiography (OCTA). Mean subject age was 8.2 ± 2.3 years in the amblyopia group and 8.6 ± 2.2 years in the control group. The mean SCP at 1 mm, 2 mm, and 3 mm zones were (in the order amblyopic eye, companion eye, control) 1.399 ± 0.088, 5.854 ± 0.195, 12.866 ± 0.346; 1.467 ± 0.084, 5.979 ± 0.182, 12.965 ± 0.321; and 1.559 ± 0.052, 6.343 ± 0.190, 13.819 ± 0.423. SCP was significantly lower in amblyopic eyes than in companion eyes and controls (P < 0.05). The mean DCP at 1 mm, 2 mm, and 3 mm zones were 1.425 ± 0.069, 6.038 ± 0.186, 13.522 ± 0.336; 1.525 ± 0.072, 6.427 ± 0.190, 14.286 ± 0.322; and 1.685 ± 0.074, 6.895 ± 0.198, 15.355 ± 0.356. DCP was significantly lower in amblyopic eyes than companion eyes and controls (P < 0.05). The mean superficial FAZ were 0.287 ± 0.091, 0.262 ± 0.092, and 0.280 ± 0.097...Continue Reading

References

Dec 17, 2014·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Mae Millicent W PeterseimRupal Trivedi
Apr 22, 2015·American Journal of Ophthalmology·Akihiro IshibazawaAkitoshi Yoshida
Jul 3, 2015·American Journal of Ophthalmology·Maddalena Quaranta-El MaftouhiChiara M Eandi
Feb 27, 2016·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·John Sloper
May 20, 2016·Journal of Ophthalmic & Vision Research·K V Chalam, Kumar Sambhav
Aug 30, 2016·Investigative Ophthalmology & Visual Science·Simon S GaoDavid Huang
Oct 16, 2016·Medicine·Adam WylęgałaEdward Wylęgała
Dec 21, 2016·International Journal of Retina and Vitreous·Nazimul Hussain, Anjli Hussain

❮ Previous
Next ❯

Citations

Feb 24, 2018·Retina·Enrico BorrelliIrena Tsui
Jul 10, 2019·Current Eye Research·Bengi DemirayakFadime Ulviye Yigit
Jan 24, 2020·Journal of Pediatric Ophthalmology and Strabismus·Esat CinarGökhan Erbakan
Jan 9, 2020·International Ophthalmology·Hatice Nur TarakciogluAbdullah Ozkaya
May 16, 2020·Journal of Binocular Vision and Ocular Motility·Robert C GunzenhauserStacy L Pineles
Mar 3, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Magdalena Niestrata-OrtizMarcin Stopa
Dec 11, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Viktoria C BrücherMaged Alnawaiseh
Jun 4, 2019·Seminars in Ophthalmology·Eric D GaierGena Heidary
Mar 20, 2019·Journal of Pediatric Ophthalmology and Strabismus·Asli InalBirsen Gokyigit
Nov 23, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Savleen KaurJaspreet Sukhija
May 23, 2020·Clinical Ophthalmology·Zerrin BayraktarMuharrem Karakaya
Mar 31, 2021·Investigative Ophthalmology & Visual Science·Noriko NishikawaAkitoshi Yoshida
Aug 6, 2021·European Journal of Ophthalmology·Rosanna GuaglianoLuciano Quaranta
Oct 4, 2021·International Journal of Retina and Vitreous·Fariba GhassemiSiamak Sabour
Dec 4, 2021·European Journal of Ophthalmology·Müjdat KarabulutAylin Karalezli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.