PMID: 11915062Mar 27, 2002Paper

Comparison of racemic bupivacaine, ropivacaine, and levo-bupivacaine for pediatric caudal anesthesia: effects on postoperative analgesia and motor block

Regional Anesthesia and Pain Medicine
G IvaniP A Lönnqvist

Abstract

To compare ropivacaine, levo-bupivacaine, and racemic bupivacaine for caudal blockade in children. Using a prospective observer blinded design, 60 sevoflurane anesthetized children (1 to 7 years) undergoing minor subumbilical surgery, were randomized to receive a caudal block (1 mL/kg) with either ropivacaine 0.2%, racemic bupivacaine 0.25%, or levo-bupivacaine 0.25%. Postoperative analgesia (number of patients needing supplemental analgesia as defined by an objective pain score [OPS] score of > or = 5; time to first analgesic demand) during the first 24 postoperative hours was chosen as the primary end-point. Early postoperative motor block (3-point scale) was assessed as a secondary end-point. All blocks were judged to be clinically successful based on the presence of adequate intraoperative and early postoperative analgesia. An OPS score > or = 5 was found in 5/20 patients in each study group. No difference regarding the time to first analgesic demand was found between the study groups. The use of ropivacaine (P =.02), but not levo-bupivacaine (P =.18), was found to be associated with less motor block during the first postoperative hour compared with racemic bupivacaine. All 3 investigated local anesthetics were found to be ...Continue Reading

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Citations

Dec 13, 2005·Der Anaesthesist·B Urbanek, S Kapral
Jun 11, 2005·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Eva JacobsonJan G Jakobsson
Apr 7, 2011·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Kemalettin KoltkaSuleyman Ozyalcin
Sep 17, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Elisabeth F A DobereinerDavid R Lardner
Feb 3, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·C Dadure, UNKNOWN Comité douleur-anesthésie locorégionale et le comité des référentiels de la Sfar
Sep 4, 2010·Regional Anesthesia and Pain Medicine·Tomoki HashimotoToshimitsu Kitajima
Aug 21, 2009·Paediatric Anaesthesia·Robert MenziesDavid G Mason
Apr 14, 2010·Anaesthesia·M D Wiles, M H Nathanson
Nov 24, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Wolfgang Zink, Bernhard M Graf
Jul 21, 2011·Current Opinion in Anaesthesiology·Per-Arne Lönnqvist
May 28, 2008·Paediatric Anaesthesia·Richard HowardUNKNOWN Association of Paediatric Anaesthetists of Great Britain and Ireland
Nov 5, 2011·Paediatric Anaesthesia·Christophe Dadure, Xavier Capdevila
Jun 13, 2002·Paediatric Anaesthesia·G Ivani
Apr 23, 2004·Acta Anaesthesiologica Scandinavica·O LiisananttiP H Rosenberg
Jul 9, 2004·Clinical and Experimental Pharmacology & Physiology·F Tonatiu Aguirre-GarayAlejandro A Nava-Ocampo
Sep 24, 2004·Paediatric Anaesthesia·Geoff P FrawleySarah Smith
Nov 9, 2012·Paediatric Anaesthesia·Zalak PatelJacqueline Tutiven
Apr 17, 2004·Paediatric Anaesthesia·Adrian Bösenberg
Nov 8, 2007·Paediatric Anaesthesia·Pablo IngelmoRoberto Fumagalli

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