Comparison of rates of bone loss from the spine measured using two manufacturers' densitometers

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
N F Peel, R Eastell

Abstract

Measurements of bone mineral density of the lumbar spine (LS-BMD) by dual-energy X-ray absorptiometry (DXA), made using different manufacturers' densitometers, differ by approximately 15%. The aim of this study was to compare the rate of bone loss from the lumbar spine measured using two manufacturers' densitometers. LS-BMD (vertebrae L2-L4) was measured using both a Lunar DPX and a Hologic QDR 1000/W in 17 postmenopausal women at baseline and 2 years. The mean rate of change of LS-BMD made using the two densitometers did not differ (DPX -0.54% per year; QDR -0.17% per year). although rates of change of LS-BMD measured using the two densitometers correlated (r = 0.47, p = 0.05), the variance of the rates of loss differed such that, in individual subjects, the difference between the rates of loss of LS-BMD, measured using the two densitometers, was related to the average rate of loss (r = 0.61, p = 0.009). For both densitometers, as bone mineral content (BMC) increased, the measured area also increased, leading to an underestimate of change in bone mineral density (BMD). This relation differed between the two densitometers such that the change in BMD was underestimated to a greater extent by QDR. We conclude that in the context ...Continue Reading

References

Sep 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N A PocockJ A Eisman
Aug 1, 1991·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R B MazessD Hans
Apr 18, 1991·The New England Journal of Medicine·C C JohnstonL J Melton
Jun 1, 1991·The Journal of Clinical Endocrinology and Metabolism·I R ReidD J Wattie
Oct 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantC Van Kuijk

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Citations

Mar 28, 1998·American Journal of Respiratory and Critical Care Medicine·R A PauwelsP Geusens
Mar 7, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K G Faulkner
Jan 8, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N A PocockJ Freund
Apr 22, 1999·The British Journal of Radiology·S Pors NielsenD Felsenberg
Nov 26, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J Reeve, M Lunt
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Anthony B HodsmanRobert Lindsay
Jul 6, 2000·Journal of Endocrinological Investigation·S AdamiR Balena
Nov 26, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R Eastell, N Peel
Feb 7, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P TothillC P Freeman
Nov 8, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·John FoxSusan Y Smith
May 8, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P Tothill, W J Hannan
Feb 6, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Gary M Kiebzak, Paul D Miller
Sep 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S L HuiH Genant
Jul 17, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Paul D MillerRoberto Pa Ci

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