Comparison of relative risks of urinary stone formation after surgery for ulcerative colitis: conventional ileostomy vs. J-pouch. A comparative study

Diseases of the Colon and Rectum
P M ChristieG L Hill

Abstract

Urinary stone formation is a widely recognized complication o f inflammatory bowel disease and the surgical management of these conditions. Previously the fecal volume and chemistry after restorative proctocolectomy with J-pouch were found to be similar to conventional panproctocolectomy with permanent ileostomy. The purpose of this study was to investigate whether the relative risks of urinary stone formation were less following J-pouch than following conventional ileostomy. The risk of urinary stone formation was determined from the chemical composition of two consecutive 24-hour urine samples in 13 patients with well-functioning ileostomies, 15 patients with well-functioning J-pouches, and 17 control volunteers. Compared with controls, ileostomy and J-pouch patients had significantly lowered urinary volumes and pH, higher concentrations of calcium and oxalate, and an increased risk of forming uric acid stones. In addition there was an increased risk of forming calcium stones in the conventional ileostomy group. This risk was found not to be present in the J-pouch group. The risks of forming uric acid stones are high for both ileostomy and J-pouch patients, but our results suggest that there will be a reduction in calcium sto...Continue Reading

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Citations

Feb 15, 2001·Surgery·D I Soybel
Jun 26, 2012·Journal of Crohn's & Colitis·Saurabh MukewarBo Shen
Feb 18, 1999·The Journal of Urology·J J SobleS B Streem
Dec 12, 2002·Endocrinology and Metabolism Clinics of North America·Elaine M Worcester
Jan 24, 2006·Annales D'urologie·M Daudon
Jun 20, 2015·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·B PradereK Bensalah
Nov 23, 2016·World Journal of Nephrology·Agapios GkentzisChandra Shekhar Biyani
May 12, 1998·The American Journal of Gastroenterology·D S PardiJ T McCarthy

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