Comparison of risk-based hepatitis C screening and the true seroprevalence in an urban prison system

Journal of Urban Health : Bulletin of the New York Academy of Medicine
Danica E KuncioKendra M Viner

Abstract

Hepatitis C virus (HCV) is the most common blood-borne infection in the USA, though seroprevalence is elevated in certain high-risk groups such as inmates. Correctional facility screening protocols vary from universal testing to opt-in risk-based testing. This project assessed the success of a risk-based HCV screening strategy in the Philadelphia Prison System (PPS) by comparing results from current testing practices during 2011-2012 (Risk-Based Screening Group) to a September 2012 blinded seroprevalence study (Philadelphia Department of Public Health (PDPH) Study Cohort). PPS processed 51,562 inmates in 2011-2012; 2,727 were identified as high-risk and screened for HCV, of whom 57 % tested HCV antibody positive. Twelve percent (n = 154) of the 1,289 inmates in the PDPH Study Cohort were anti-HCV positive. Inmates ≥30 years of age had higher rates of seropositivity in both groups. Since only 5.3 % of the prison population was included in the Risk-Based Screening Group, an additional 4,877 HCV-positive inmates are projected to have not been identified in 2011-2012. Gaps in case identification exist when risk-based testing is utilized by PPS. A more comprehensive screening model such as opt-out universal testing should be conside...Continue Reading

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Citations

Jul 19, 2016·Lancet·Josiah D RichFrederick L Altice
Nov 7, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Megan G HofmeisterA Blythe Ryerson
Sep 15, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·UNKNOWN AASLD-IDSA HCV Guidance Panel
Jul 7, 2019·Harm Reduction Journal·Desmond CrowleyJohn S Lambert
Dec 10, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Marc G GhanyUNKNOWN AASLD-IDSA Hepatitis C Guidance Panel
May 12, 2016·Public Health Reports·Ben T SchoenbachlerAnne C Spaulding
Jan 1, 2020·Current Hepatology Reports·Tatyana KushnerArthur Y Kim
Feb 11, 2020·JHEP Reports : Innovation in Hepatology·Elizabeth C VernaRobert S Brown

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