Comparison of Sagittal FSE T2, STIR, and T1-Weighted Phase-Sensitive Inversion Recovery in the Detection of Spinal Cord Lesions in MS at 3T.

AJNR. American Journal of Neuroradiology
P Alcaide-LeonA Bharatha

Abstract

Determining the diagnostic accuracy of different MR sequences is essential to design MR imaging protocols. The purpose of the study was to compare 3T sagittal FSE T2, STIR, and T1-weighted phase-sensitive inversion recovery in the detection of spinal cord lesions in patients with suspected or definite MS. We performed a retrospective analysis of 38 patients with suspected or definite MS. Involvement of the cervical and thoracic cord segments was recorded on sagittal FSE T2, STIR, and T1-weighted phase-sensitive inversion recovery sequences independently by 2 readers. A consensus criterion standard read was performed with all sequences available. Sensitivity, specificity, and interobserver agreement were calculated for each sequence. In the cervical cord, the sensitivity of T1-weighted phase-sensitive inversion recovery (96.2%) and STIR (89.6%) was significantly higher (P < .05) than that of FSE T2 (50.9%), but no significant difference was found between T1-weighted phase-sensitive inversion recovery and STIR. In the thoracic cord, sensitivity values were 93.8% for STIR, 71.9% for FSE T2, and 50.8% for T1-weighted phase-sensitive inversion recovery. Significant differences were found for all comparisons (P < .05). No differences...Continue Reading

References

Jul 1, 1994·Radiology·D J MikulisB P Poncelet
Jun 1, 1996·Brain : a Journal of Neurology·J W ThorpeD H Miller
Apr 30, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Qing X YangWei Chen
May 30, 2006·Neuroimaging Clinics of North America·Vaishali V PhalkeDouglas J Quint
Oct 14, 2008·Seminars in Musculoskeletal Radiology·Peter FriesGuenther Schneider
Nov 3, 2010·European Journal of Radiology·Cristina Philpott, Peter Brotchie
Sep 22, 2012·AJR. American Journal of Roentgenology·Christopher G FilippiTrevor Andrews
Jun 15, 2013·AJNR. American Journal of Neuroradiology·G NairD S Reich

❮ Previous
Next ❯

Citations

Sep 13, 2016·Seminars in Ultrasound, CT, and MR·Alex Rovira, Cristina Auger
Jan 23, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Jiwon Oh, Nancy L Sicotte
Oct 28, 2019·Journal of Neurology·S MirafzalJ Savatovsky
Jan 24, 2018·Neurology. Neuroimmunology and Neuroinflammation·Paula Alcaide-LeonJiwon Oh
Mar 7, 2020·Expert Review of Neurotherapeutics·Maria A RoccaMassimo Filippi
May 2, 2019·Therapeutic Advances in Neurological Disorders·Marcello MocciaOlga Ciccarelli
Apr 20, 2019·AJNR. American Journal of Neuroradiology·S SuthiphosuwanJ Oh
Apr 19, 2017·Current Treatment Options in Neurology·Suradech SuthiphosuwanJiwon Oh
May 14, 2016·Current Opinion in Neurology·Alex Rovira, Nicola de Stefano
Nov 19, 2020·Brain Sciences·Yongsheng ChenEvanthia Bernitsas
Feb 6, 2020·Journal of Neuroradiology. Journal De Neuroradiologie·Jean-Christophe BrissetUNKNOWN Collaborators
Oct 19, 2020·Revue neurologique·S LeguyA Kerbrat
Jun 18, 2021·Lancet Neurology·Mike P WattjesUNKNOWN North American Imaging in Multiple Sclerosis Cooperative MRI guidelines working group
Jul 20, 2021·Expert Review of Neurotherapeutics·Àlex Rovira, Cristina Auger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JBR-BTR : Organe De La Société Royale Belge De Radiologie (SRBR) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (KBVR)
Ph DemaerelG Wilms
© 2022 Meta ULC. All rights reserved