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Comparison of somatic mutation calling methods in amplicon and whole exome sequence data

BMC Genomics

Apr 1, 2014

Huilei XuYexun Wang

Abstract

High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA sequencing. Although numerous studies have compared the perform...read more

Mentioned in this Paper

GCAT gene
Crossbreeding
Dideoxy Chain Termination DNA Sequencing
Gene Amplification Technique
Sequencing
Myeloid Leukemia, Chronic
Mutation Abnormality
Gene Amplification Abnormality
Neoplasm, Residual
GC acyltransferase
6
300
Paper Details
References
  • References25
  • Citations33
123
  • References25
  • Citations33

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Comparison of somatic mutation calling methods in amplicon and whole exome sequence data

BMC Genomics

Apr 1, 2014

Huilei XuYexun Wang

PMID: 24678773

DOI: 10.1186/1471-2164-15-244

Abstract

High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA sequencing. Although numerous studies have compared the perform...read more

Mentioned in this Paper

GCAT gene
Crossbreeding
Dideoxy Chain Termination DNA Sequencing
Gene Amplification Technique
Sequencing
Myeloid Leukemia, Chronic
Mutation Abnormality
Gene Amplification Abnormality
Neoplasm, Residual
GC acyltransferase
6
300

Similar Papers Found In These Feeds

Paper Details
References
  • References25
  • Citations33
123
  • References25
  • Citations33
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