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Comparison of somatic mutation calling methods in amplicon and whole exome sequence data

BMC Genomics

Mar 28, 2014

Huilei XuYexun Wang

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Abstract

High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA sequencing. Although numerous studies have compared the perform...read more

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  • Comparison of somatic mutation calling methods in amplicon and whole exome sequence data

    BMC Genomics

    Mar 28, 2014

    Huilei XuYexun Wang

    PMID: 24678773

    DOI: 10.1186/1471-2164-15-244

    Abstract

    High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA sequencing. Although numerous studies have compared the perform...read more

    6
    289

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    • Citations27
    • References25
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