PMID: 26369Apr 1, 1978Paper

Comparison of speed of onset of fazadinium, pancuronium, tubocurarine and suxamethonium

British Journal of Anaesthesia
C L Blackburn, M Morgan


Under light general anaesthesia the speed of onset of action of fazadinium, pancuronium, tubocurarine and suxamethonium has been assessed by measuring the decrease in the twitch height of the adductor pollicis muscle following administration of the drugs. Suxamethonium produced 95% depression of the twitch height significantly faster than any of the other drugs, while the onset of fazadinium was significantly more rapid than that of the other non-depolarizing neuromuscular blocking drugs.


Jul 1, 1985·Canadian Anaesthetists' Society Journal·J Lerman, A A Kiskis
Sep 1, 1986·Canadian Anaesthetists' Society Journal·F DonatiD R Bevan
Nov 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P I ReynoldsA F VanDerSpek
May 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·F Donati
Jun 1, 1979·Anaesthesia·J A CouchD M Magauran
Apr 1, 1991·Anaesthesia·A P Kent, J M Hunter
Nov 1, 1978·British Journal of Clinical Pharmacology·R Hughes, J P Payne
Aug 1, 1979·Acta Anaesthesiologica Scandinavica·S Z HussainA T Birmingham
Feb 1, 1993·Acta Anaesthesiologica Scandinavica·S P Roberts, B J Pollard
Dec 1, 1981·The Australian and New Zealand Journal of Surgery·J Gomez-ArnauF Avello
Jan 1, 1991·DICP : the Annals of Pharmacotherapy·G E LarijaniA G Jacobi

Related Concepts

Nerve-Muscle Preparation
Pancuronium Curamed
Pyridinium Compounds
Tubocurarine Chloride

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Laryngeal Neoplasms

Laryngeal Neoplasms occur in the Larynx and are typically associated with smoking and alcohol consumption. Discover the latest research on Laryngeal Neoplasms here.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.