Comparison of standard renal denervation procedure versus novel distal and branch vessel procedure with brachial arterial access.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
Ivo PetrovIana Simova

Abstract

We assessed a novel approach to percutaneous renal denervation for uncontrolled hypertension consisting of ablation beyond the proximal main renal artery (Y-pattern), including the primary branches, and compared it to the standard procedure applied only within the main vessel. We also assessed the safety and practicality of a brachial access approach. Renal denervation was performed on 119 consecutive patients (60 ± 13 years). In 68 of the patients, femoral arterial vascular approach was used and in 51 brachial. In 80 patients treated with the standard ablation, 12.0 ± 3.0 total ablations (both sides) were applied while 20.4 ± 3.9 total ablations were delivered for the group of 39 patients with Y-pattern denervation (P < 0.001). Technically successful renal denervation was achieved in all patients. Office blood-pressure levels at baseline were 170 ± 17/93 ± 10 mm Hg for the standard group and 169 ± 13/96 ± 9 mm Hg for the Y-pattern group. No major adverse events occurred during the procedure or in the postprocedural in-hospital period. Renal denervation was associated with significant decreases in both office and ambulatory systolic and diastolic blood pressure in both groups. The reduction in 24-hour mean ambulatory systolic b...Continue Reading

Citations

Nov 9, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Atsushi SakaokaKenichi Sakakura
Jan 10, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nachiket J PatelRichard R Heuser
Feb 11, 2020·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Raymond R TownsendGiuseppe Mancia
Sep 12, 2018·Current Hypertension Reports·Raymond R Townsend, Paul A Sobotka
Aug 23, 2020·Animals : an Open Access Journal From MDPI·Armando Pérez de PradoFelipe Fernández-Vázquez
Feb 16, 2021·Progress in Cardiovascular Diseases·Lucas LauderFelix Mahfoud
Nov 23, 2021·The Cochrane Database of Systematic Reviews·Anna PisanoDavide Bolignano

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