Comparison of standard vs high-definition, wide-angle colonoscopy for polyp detection: a randomized controlled trial

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
G TriboniasG A Paspatis

Abstract

We sought to compare the performance of colonoscopy using a high-definition, wide-angle endoscope vs a standard colonoscope for the detection of polyps. A total of 390 patients were prospectively randomized into high-definition colonoscopy group (HD, n = 193) and standard colonoscopy group (SC, n = 197). Analysis demonstrated that there were significant differences between the two groups, as far as the overall rate of polyps (SC, 1.31 ± 1.90; HD, 1.76 ± 2.31; P = 0.03) and the rate of small hyperplastic polyps (size < 5 mm; SC, 0.10 ± 0.36; HD, 0.25 ± 0.61; P = 0.003) were concerned. No significant differences between the two groups were observed, regarding large polyps (size ≥ 10 mm; SC, 0.39 ± 0.89; HD, 0.48 ± 0.80; P = 0.10), medium polyps (10 mm > size ≥ 5 mm; SC, 0.60 ± 1.46; HD, 0.58 ± 1.25; P = 0.31) and small polyps (size < 5 mm; SC, 0.32 ± 0.86; HD, 0.71 ± 1.65; P = 0.09). Similarly, no significant differences were demonstrated in the detection rate of adenomas and hyperplastic polyps, large adenomas, medium adenomas, small adenomas and large and medium hyperplastic polyps. High-definition colonoscopy led to a significant increase in the polyp detection.

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Citations

Jun 19, 2013·Current Gastroenterology Reports·P UrquhartN Marcon
May 14, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G A PaspatisG Chlouverakis
Nov 3, 2011·World Journal of Gastroenterology : WJG·Tolga ErimFernando Castro
Nov 9, 2011·Journal of General Internal Medicine·Dimitra Dodou, Joost C F de Winter
Jul 10, 2014·Surgical Endoscopy·Elisabeth WaldmannMonika Ferlitsch
Mar 8, 2014·World Journal of Gastroenterology : WJG·Vincent K DikPeter D Siersema
Sep 7, 2011·Nature Reviews. Gastroenterology & Hepatology·Yark Hazewinkel, Evelien Dekker
Jul 26, 2011·Current Opinion in Gastroenterology·Krishna C Vemulapalli, Douglas K Rex
Dec 3, 2011·Current Opinion in Gastroenterology·Susan G Coe, Michael B Wallace
Aug 13, 2013·Gastroenterology Clinics of North America·Zilla H Hussain, Heiko Pohl
Mar 3, 2012·Gastrointestinal Endoscopy·Reena V ChokshiJean S Wang
Jun 4, 2016·Current Gastroenterology Reports·Selvi ThirumurthiGottumukkala S Raju
Jun 12, 2014·United European Gastroenterology Journal·Gaius Longcroft-WheatonPradeep Bhandari
Aug 19, 2014·World Journal of Gastrointestinal Endoscopy·Johannes Wilhelm ReyArthur Hoffman
Feb 1, 2018·Therapeutic Advances in Gastroenterology·Wee Sing Ngu, Colin Rees
Nov 3, 2010·Current Opinion in Gastroenterology·Silvio W de Melo, Michael B Wallace
Jun 12, 2016·Surgical Endoscopy·Nezar Y JrebiMartin Luchtefeld
Jan 17, 2015·World Journal of Gastroenterology : WJG·Sarah K McGillSubhas Banerjee
Mar 5, 2016·World Journal of Gastroenterology : WJG·Jeong-Yeop SongMoon Sung Lee

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