Comparison of stellate ganglion block with intravascular infusion of prostaglandin E1 on brachial artery blood flow in dogs

Anesthesia and Analgesia
Y Okuda, T Kitajima

Abstract

We sought to determine whether sympathetic blockade or infusion of prostaglandin E1 (PGE1) is better for vasodilation. We measured brachial artery blood flow (BABF) in 10 mongrel dogs using an ultrasonic time flowmeter to compare the effects of stellate ganglion block (SGB) and intravascular infusion of PGE1. The experimental protocol was designed as follows: 1) intravenous (IV) infusion of PGE1 at a rate of 10 ng x kg(-1) x min(-1) for 10 min, 2) IV infusion of PGE1 at a rate of 150 ng x kg(-1) x min(-1) for 10 min, 3) intraarterial infusion of PGE1 at a rate of 0.1 ng x kg(-1) x min(-1) for 10 min, 4) SGB with 0.5% mepivacaine 1.0 mL was used as a sympathetic blockade. These procedures were successively performed on each dog. Mean arterial pressure (MAP), heart rate (HR), and BABF were measured before and after each procedure for 40 min. MAP and HR did not change significantly after the procedures. BABF increased significantly after IV infusion of PGE1 150 ng x kg(-1) x min(-1), intraarterial infusion of PGE1 and SGB, reaching maximums of 157%, 174%, and 171% 10 min after IV infusion of PGE1 150 ng x kg(-1) x min(-1), intraarterial infusion of PGE1 and SGB compared with the prevalues, respectively. These data indicate that sy...Continue Reading

References

Oct 9, 1976·Lancet·L A Carlson, A G Olsson
Dec 1, 1992·Anesthesia and Analgesia·A Owen-Falkenberg, K S Olsen
Sep 1, 1985·The British Journal of Surgery·L T Cotton, F W Cross
Jan 1, 1970·The British Journal of Surgery·H J TerryG W Taylor
Aug 1, 1980·Acta Anaesthesiologica Scandinavica·J ModigG Karlström
Oct 1, 1994·British Medical Bulletin·G D LoweD P Leiberman

❮ Previous
Next ❯

Citations

Oct 10, 2009·The Bulletin of Tokyo Dental College·Yui TerakawaYuzuru Kaneko

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.