Comparison of stress perfusion MRI and SPECT for detection of myocardial ischemia in patients with angiographically proven three-vessel coronary artery disease

AJR. American Journal of Roentgenology
Se-Yeong ChungSang Il Choi

Abstract

This study aims to evaluate the diagnostic value of stress perfusion MRI and SPECT for the detection of myocardial ischemia in patients with angiographically proven three-vessel coronary artery disease. We retrospectively enrolled 78 patients with angiographically proven three-vessel coronary artery disease who underwent both stress perfusion MRI and SPECT within 4 weeks of each other. Image analysis was performed to compare the diagnostic value of stress perfusion MRI with that of SPECT; coronary angiography was used as the reference standard. The statistical significance of the difference between stress perfusion MRI and SPECT was evaluated by use of the paired McNemar test. Myocardial ischemia was detected significantly more often by stress perfusion MRI than by SPECT, with more abnormal segments (mean +/- SD, 10.1 +/- 3.6 vs 4.9 +/- 2.6; p < 0.001) and abnormal vascular territories (2.55 +/- 0.5 vs 1.64 +/- 0.7; p < 0.001) identified per patient. The overall sensitivity for identifying perfusion defects in three vascular territories was higher for stress perfusion MRI than for SPECT (84.6% vs 55.1%; p < 0.001). The sensitivity of stress perfusion MRI and SPECT for detecting any perfusion defect per patient was 100% and 96.2...Continue Reading

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Citations

May 3, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Jeanette Schulz-MengerEike Nagel
Apr 8, 2014·The International Journal of Cardiovascular Imaging·Mohammad R HojjatiBenjamin Y C Cheong
Nov 10, 2010·Journal of Cardiovascular Translational Research·Luís Henrique Wolff GowdakJosé Eduardo Krieger
Jul 24, 2015·Current Atherosclerosis Reports·Nikolaos Kakouros, Jeffrey J Rade
May 23, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Shu YokotaJan Paul Ottervanger
Jul 6, 2013·European Journal of Radiology·Kughan GunaratnamJohn Troupis
Jul 20, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Shazia T HussainEike Nagel
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Apr 22, 2017·Nuclear Medicine Communications·Julien PriamoRené Nkoulou
Mar 12, 2019·Kardiologiia·Ya K Rustamova
Sep 15, 2017·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yohei YamauchiNobukazu Ishizaka
Sep 17, 2020·La Radiologia medica·Vitaliano Buffa, Paolo Di Renzi
Dec 20, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Dong Jin ImBae Young Lee
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Sep 27, 2018·European Journal of Nuclear Medicine and Molecular Imaging·V Ralph McCready, Sabina Dizdarevic
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Jun 11, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Hajime Sakuma, Masaki Ishida

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