PMID: 9420743Nov 1, 1994Paper

Comparison of technetium 99m Q12 and thallium 201 for detection of angiographically documented coronary artery disease in humans

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
M C GersonR A Walsh

Abstract

99mTc-labeled Q12 (99mTc-Q12) is a new imaging agent that produces myocardial visualization in humans. This study examined the hypothesis that a 100-minute rest-exercise tomographic imaging protocol after injection of 99mTc-Q12 can be used to detect the presence or absence of coronary artery stenoses. Imaging with 201Tl and 99mTc-Q12 was performed in 20 patients with angiographically documented coronary artery disease and 10 "normal" subjects including two patients with chest pain and normal coronary arteriograms and eight subjects with a very low likelihood of occlusive coronary disease. 99mTc-Q12 was imaged beginning 15 minutes after injection at rest and with exercise. In the 20 patients, a corresponding myocardial defect was detected in blinded fashion in 18 with 201Tl and 17 with 99mTc-Q12 (difference not significant). Of 10 patients without evidence of coronary disease, nine had a normal 201Tl scan and eight had a normal 99mTc-Q12 scan (difference not significant). Agreement of 99mTc-Q12 and 201Tl imaging for detection of regional myocardial perfusion defects was excellent (kappa = 0.88). Identification of the presence or absence of angiographically documented coronary disease in individual coronary artery distributions w...Continue Reading

References

Jul 1, 1976·Medical Physics·S R ThomasJ G Kereiakes
Jan 1, 1983·European Journal of Nuclear Medicine·M C GersonC C Williams
Oct 2, 1981·Science·E DeutschS J Lukes
Aug 1, 1981·The American Journal of Cardiology·R F DunnE H Botvinick
Mar 1, 1994·Circulation·M C GersonR C Elder
Sep 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R C RoheH R Maxon
Jan 1, 1979·Annals of the ICRP

❮ Previous
Next ❯

Citations

Mar 1, 1997·European Journal of Nuclear Medicine·R M AignerG Wolf
Jun 5, 2002·Annals of Nuclear Medicine·Yasushi Arano
Oct 1, 1996·Clinical Radiology·M G Gunning, S R Underwood
Jun 6, 2000·Advanced Drug Delivery Reviews·Y Arano
Sep 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R C RoheH R Maxon
May 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M C GersonR A Walsh
Jul 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R C HendelM C Gerson
Mar 17, 2001·Current Problems in Cardiology·D S BermanG Germano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
M C GersonR A Walsh
International Journal of Nuclear Medicine and Biology
S M GuptaT W Crucitti
Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Laurent PhilippeGuillaume Divry
© 2021 Meta ULC. All rights reserved