Because discrepancies about baroreflex sensitivity in essential hypertension may have resulted from the use of different measurement techniques, we assessed the extent to which the results of different techniques agree in the same subjects. The eight techniques studied were the change in RR interval per unit change in systolic pressure during the Valsalva maneuver, upon release of the Valsalva maneuver, after injection of phenylephrine and after injection of nitroglycerin; the changes in RR interval and in systolic pressure per mm Hg externally applied neck suction; and the changes in RR interval and systolic pressure per mm Hg externally applied neck pressure. The average intercorrelation among these measures in 30 subjects was statistically significant (r = 0.36, p less than 0.01), but suggests that variance in one measure accounted for an average of about 13% of the variance in other measures. Standard deviations among subjects were often as large as the mean, indicating important interindividual variability as well. These findings demonstrate that baroreflex sensitivity varies widely among subjects and that different techniques for measuring baroreflex sensitivity probably measure different aspects of baroreflex function.
Valsalva constrictor and heart rate reflexes in subjects with essential hypertension and with normal blood pressure
Does the baroreceptor-heart rate reflex indicate the capacity of the arterial baroreceptors to control blood pressure?
Cardiovascular autonomic dysfunction in normotensive awake subjects with obstructive sleep apnoea syndrome
Effect of postural changes on arterial baroreflex sensitivity assessed by the spontaneous sequence method and Valsalva manoeuvre in healthy subjects
Low frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation
Baroreflex function during 45-degree passive head-up tilt before and after long-term thiazide therapy in the elderly with systolic systemic hypertension
Treatment with raloxifene and 17beta-estradiol differentially modulates nitric oxide and prostanoids in venous endothelium and platelets of ovariectomized pigs
Contribution of baroreflex sensitivity and vascular reactivity to variable haemodynamic responses to cocaine in conscious rats
Effect of acute atenolol on short-term blood pressure variability and baroreflex sensitivity in rats
Cardiac baroreflex gain is frequency dependent: insights from repeated sit-to-stand maneuvers and the modified Oxford method
Altered autonomic cardiovascular regulation after combined deep and superficial cervical plexus blockade for carotid endarterectomy
Quantitative indices of baroreflex-sympathoneural function: application to patients with chronic autonomic failure
Differential effects of azelnidipine and amlodipine on sympathetic nerve activity in patients with primary hypertension
Do autonomic cardiovascular reflexes predict the nocturnal rise in blood pressure in obstructive sleep apnea syndrome?
Spectral analysis of heart rate variability reveals an enhanced sympathetic activity in narcolepsy with cataplexy
The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: a versatile in vivo model in cardiovascular safety research
Supine low-frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation
Decreased renal sympathetic activity in response to cardiac unloading with nitroglycerin in patients with heart failure
Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension
Response patterns of arterial pressure and heart period to Mueller manoeuvre and their comparison to those of Valsalva manoeuvre
Blood pressure responses after carotid surgery: relationship to postoperative baroreceptor sensitivity
Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke
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