Comparison of the capacity of two biotic ligand models to predict chronic copper toxicity to two Daphnia magna clones and formulation of a generalized bioavailability model

Environmental Toxicology and Chemistry
Tina Van RegenmortelKarel A C De Schamphelaere

Abstract

Although it is increasingly recognized that biotic ligand models (BLMs) are valuable in the risk assessment of metals in aquatic systems, the use of 2 differently structured and parameterized BLMs (1 in the United States and another in the European Union) to obtain bioavailability-based chronic water quality criteria for copper is worthy of further investigation. In the present study, the authors evaluated the predictive capacity of these 2 BLMs for a large dataset of chronic copper toxicity data with 2 Daphnia magna clones, termed K6 and ARO. One BLM performed best with clone K6 data, whereas the other performed best with clone ARO data. In addition, there was an important difference between the 2 BLMs in how they predicted the bioavailability of copper as a function of pH. These modeling results suggested that the effect of pH on chronic copper toxicity is different between the 2 clones considered, which was confirmed with additional chronic toxicity experiments. Finally, because fundamental differences in model structure between the 2 BLMs made it impossible to create an average BLM, a generalized bioavailability model (gBAM) was developed. Of the 3 gBAMs developed, the authors recommend the use of model gBAM-C(uni), which c...Continue Reading

References

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Jan 5, 2002·Aquatic Toxicology·Brita T A MuyssenBart T A Bossuyt
Jan 31, 2002·Environmental Science & Technology·Karel A C de Schamphelaere, Colin R Janssen
Oct 14, 2003·Environmental Toxicology and Chemistry·Karel A De SchamphelaereColin R Janssen
Jun 8, 2004·Environmental Toxicology and Chemistry·Karel A C De Schamphelaere, Colin R Janssen
Sep 21, 2004·Environmental Toxicology and Chemistry·Karel A C De Schamphelaere, Colin R Janssen
Apr 6, 2005·Environmental Pollution·Bart T A Bossuyt, Colin R Janssen
Aug 23, 2005·Environmental Toxicology and Chemistry·Karel A C De SchamphelaereColin R Janssen
May 18, 2006·Environmental Toxicology and Chemistry·Matthew W WheelerA John Bailer
Aug 15, 2006·Environmental Science & Technology·Karel A C De Schamphelaere, Colin R Janssen
Dec 25, 2008·Environmental Toxicology and Chemistry·Nele M E DeleebeeckColin R Janssen

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Citations

Dec 16, 2016·Environmental Toxicology and Chemistry·Cecília M S PereiraKarel A C De Schamphelaere
Dec 28, 2019·Environmental Toxicology and Chemistry·Kevin V BrixRuss Erickson
Dec 28, 2019·Environmental Toxicology and Chemistry·Christopher A MebaneChris M Wood
Jun 24, 2020·Environmental Toxicology and Chemistry·Charlotte NysKarel A C De Schamphelaere
Jul 18, 2018·Water Research·Nathan J TomczykKrista A Capps
May 26, 2021·The Science of the Total Environment·Jiwoong ChungJong-Hyeon Lee

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