PMID: 3761110Sep 1, 1986Paper

Comparison of the cholesteryl ester composition of human milk from preterm and term mothers

Journal of Pediatric Gastroenterology and Nutrition
J BitmanM Hamosh

Abstract

Milk was obtained on postpartum days 2-3 (colostrum) and days 7, 21, 42, and 84 from mothers of 18 very premature (VPT, 26-30 weeks gestational age), 28 premature (PT, 31-36 weeks), and 6 term (T, 37-40 weeks) infants. Lipids were extracted in chloroform-methanol and analyzed by thin-layer (TLC) and gas liquid chromatography (GLC). Fatty acid composition of cholesteryl esters was determined by GLC after isolation of cholesteryl esters by preparative TLC and preparation of methyl esters of the constituent fatty acids. As lactation progressed, amounts of total cholesterol and cholesteryl esters declined. Cholesteryl esters decreased from about 5 mg/dl in colostrum to 1 mg/dl in mature milk. The cholesteryl esters of colostrum from mothers of premature infants were different in fatty acid composition from those of term infants. Proportions of medium-chain saturated fatty acids (12:0, 14:0, 16:0) of preterm colostrum (VPT and PT) were considerably lower than in term colostrum: 23% of total fatty acids versus 35%. Proportions of 18:3, 20:3, and 20:4 of VPT (5.6%) and PT (6.2%) colostrum were considerably higher than T colostrum (1.8%). The fatty acid composition of cholesteryl esters of VPT, PT, and T milk was relatively similar at ...Continue Reading

Citations

Nov 1, 1992·Lipids·M Hamosh, J Bitman
May 22, 2010·Analytical and Bioanalytical Chemistry·Michael A JansenEdith Porter
Mar 1, 1996·Progress in Lipid Research·R G Jensen
Dec 27, 2007·Plastic and Reconstructive Surgery·Scott L SpearUNKNOWN Inamed Silicone Breast Implant U.S. Study Group
May 1, 1990·Journal of Dairy Science·J Bitman, D L Wood
Feb 1, 2000·Lipids·R G Jensen
Aug 31, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Amy GatesBrian K Stansfield
Aug 16, 2016·The British Journal of Nutrition·Catherine BoyceGemma McLeod

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