PMID: 9424251Jun 1, 1997Paper

Comparison of the DNA-GEN Probe PACE 2 method and the LCR method for the detection of Chlamydia trachomatis in the female genital tract

Ceská gynekologie
T BinderI Kuklová

Abstract

Comparison of two methods of so-called rapid assessment of Chlamydia trachomatis in the urogenital system, i.e. the hybridization method GEN-Probe PACE 2 and the amplification LCR (ligase chain reaction) method. In 1995-1996 the authors made a screening examination to detect Chlamydiae in the urogenital tract by means of the hybridization method GEN-Probe PACE 2 and the amplification LCR method in selected groups of patients of the Second Gynaecological and Obstetric Clinic, First Faculty Hospital, Prague. The methods were evaluated as to their sensitivity. The examinations of the samples were made in the serological laboratory of the First Dermatological Clinic of the First Faculty Hospital Charles University, Prague. The amplification method is twice as sensitive as the hybridization method.

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