Comparison of the effect of oral care with four different antiseptics to prevent ventilator-associated pneumonia in adults: protocol for a network meta-analysis

Systematic Reviews
Zhigang ZhangJinhui Tian

Abstract

Ventilator-associated pneumonia (VAP) is defined as the occurrence of pneumonia in patients receiving mechanical ventilation for more than 48 h after endotracheal intubation. The implementation of effective oral care with antiseptics may reduce the incidence of ventilator-associated pneumonia. However, previous studies have been unclear about the best antiseptic for this purpose. Therefore, present protocol proposed to perform a network meta-analysis to evaluate the efficacy of different antiseptics to prevent ventilator-associated pneumonia. We will search CNKI, WanFang database, PubMed, Web of Science, Cochrane Library, EMBASE, SinoMed from their inception to March 2016. There are no restrictions on language, publication year, or publication type. Only randomized clinical trials (RCTs) with antiseptics to prevent ventilator-associated pneumonia will be considered. Study selection and data collection will be independently performed by two reviewers. Risk of bias assessments will be completed using the Cochrane risk of bias scale. The primary outcome is VAP morbidity. A network meta-analysis will be conducted to compare the effect of four different antiseptics on patient-relevant efficacy. Subgroup analyses will be performed by...Continue Reading

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Citations

Jan 30, 2019·Journal for Specialists in Pediatric Nursing : JSPN·Youngmee AhnMin Sohn

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BETA
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RevMan
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PRISMA
Stata13
Excel
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