Comparison of the effectivity of oral and intra-articular administration of tenoxicam in patients with knee osteoarthritis

Brazilian Journal of Anesthesiology
Mesut ErbasHuseyin Toman

Abstract

Tenoxicam is widely used in osteoarthritis treatment and we aimed to compare the effectivity of oral and intra-articular administration of tenoxicam in osteoarthritis treatment. This study was performed between 2011 and 2012 by retrospectively analyzing and comparing the findings of 60 patients who were clinically and radiologically diagnosed with knee degenerative osteoarthritis in Bünyan state hospital pain policlinic. 60 patients included in the study were divided into two groups. The first group (tenoxicam IA, n=30) included patient findings of those subjected to intra-articular injection of 20mg tenoxicam to the knee once a week for three weeks and the second group (oral tenoxicam, n=30) included patients who were administered 20mg oral tenoxicam once a day for three weeks. All patients were clinically evaluated pre-treatment and in the 1st week, 1st month and 3rd month post-treatment according to specified criteria. Twenty two of 60 patients included in the study were male and 38 were female. In both groups significant improvements were detected in all of the observed parameters: visual analog scale, Western Ontario McMaster Osteoarthritis Index (pain, physical activity, knee stiffness) and Lequesne index scores and in th...Continue Reading

References

Jan 1, 1994·Clinical Pharmacokinetics·O G Nilsen
Aug 12, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S T ColbertM McCarroll
Oct 19, 2006·Cleveland Clinic Journal of Medicine·David H Neustadt
Jan 30, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Roberto VanelliFrancesco Benazzo

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