Comparison of the effects of sugammadex and neostigmine on hospital stay in robot-assisted laparoscopic prostatectomy: a retrospective study.

BMC Anesthesiology
Byung-Hun MinYoung-Tae Jeon

Abstract

Sugammadex reduces postoperative complications. We sought to determine whether it could reduce the length of hospital stay, post-anesthetic recovery time, unplanned readmission, and charges for patients who underwent robot-assisted laparoscopic prostatectomy (RALP) when compared to neostigmine. This was a retrospective observational study of patients who underwent RALP between July 2012 and July 2017, in whom rocuronium was used as a neuromuscular blocker. The primary outcome was the length of hospital stay after surgery in patients who underwent reversal with sugammadex when compared to those who underwent reversal with neostigmine. The secondary outcomes were post-anesthetic recovery time, hospital charges, and unplanned readmission within 30 days after RALP. In total, 1430 patients were enrolled. Using a generalized linear model in a propensity score-matched cohort, sugammadex use was associated with a 6% decrease in the length of hospital stay (mean: sugammadex 7.7 days vs. neostigmine 8.2 days; odds ratio [OR] 0.94, 95% confidence interval [CI] [0.89, 0.98], P = 0.008) and an 8% decrease in post-anesthetic recovery time (mean: sugammadex 36.7 min vs. neostigmine 40.2 min; OR 0.92, 95% CI [0.90, 0.94], P < 0.001) as compare...Continue Reading

References

Aug 12, 2005·The Journal of Urology·Akshay BhandariMani Menon
Jul 19, 2008·Anesthesia and Analgesia·Glenn S MurphyJeffery S Vender
Nov 13, 2015·Anaesthesia·A Abad-GurumetaUNKNOWN Evidence Anaesthesia Review Group
Mar 1, 2016·Korean Journal of Hepato-biliary-pancreatic Surgery·Jae Uk ChongKyung Sik Kim
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Apr 14, 2017·British Journal of Anaesthesia·D A MaerzD M Gainsburg
May 13, 2017·Journal of Clinical Anesthesia·Michele CarronCarlo Ori

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