Comparison of the efficacy and safety of shockwave lithotripsy, retrograde intrarenal surgery, percutaneous nephrolithotomy, and minimally invasive percutaneous nephrolithotomy for lower-pole renal stones: A systematic review and network meta-analysis.

Medicine
Sheng-Han TsaiWei-Te Lei

Abstract

Shock wave lithotripsy (SWL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL), and minimally invasive PCNL are currently therapeutic options for lower-pole renal stones (LPS). However, the optimal treatment for LPS remains unclear. A comprehensive evaluation of the efficacy and safety of each intervention is needed to inform clinical decision-making. This study aimed at assessing the efficacy and safety of different interventions for LPS. PubMed, Embase, ScienceDirect, ClinicalKey, Cochrane Library, ProQuest, Web of Science, and ClinicalTrials.gov were searched from inception to December 6th 2018. Only randomized controlled trials (RCTs) including the patients treated for LPS were included. The frequentist models of network meta-analysis were used to compare the effect sizes. The primary outcome was stone free rate, and the secondary outcomes were overall complication rate, major complication rate, retreatment rate, and auxiliary procedure rate. This study included 13 RCTs comprising 1832 participants undergoing 6 different interventions, including RIRS, PCNL, Mini-PCNL, Micro-PCNL, SWL, and conservative observation. PCNL had the best stone free rate (odds ratio [OR] = 3.45, 95% confidence interval [CI...Continue Reading

References

Sep 28, 2004·Statistics in Medicine·G Lu, A E Ades
Sep 30, 2009·Journal of Endourology·Petros G SountoulidesRalph V Clayman
Feb 23, 2010·The Journal of Urology·Emrah YurukAhmet Tefekli
Apr 11, 2012·European Urology·Jean J M C H de la RosetteUNKNOWN CROES PCNL Study Group
Apr 14, 2012·European Urology·Charles D ScalesUNKNOWN Urologic Diseases in America Project
Sep 26, 2014·BMJ : British Medical Journal·Milo A PuhanUNKNOWN GRADE Working Group
Sep 28, 2014·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Yu-Kang Tu
Feb 14, 2015·The Journal of Urology·Andreas SkolarikosJean de la Rosette
Sep 8, 2015·European Urology·Christian TürkThomas Knoll
Nov 12, 2015·Current Opinion in Urology·Cecilia Maria CraccoCesare Marco Scoffone
Nov 1, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·J P HigginsG Salanti
Nov 9, 2016·International Journal of Surgery·Thomas Tailly, John Denstedt

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Software Mentioned

ProQuest
MicroPCNL
STATA

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