Comparison of the efficacy of three different chlorhexidine preparations in decreasing the levels of mutans streptococci in saliva and interdental plaque

Caries Research
S Twetman, L G Petersson

Abstract

The aim of the present study was to evaluate and compare the effects of three different chlorhexidine (CHX)-containing preparations on mutans streptococci (MS) levels in interdental plaque and whole saliva. Ninety-three healthy school-children (8-10 years old) with high scores of salivary MS were selected by a screening procedure and randomised into three equally sized groups. MS were enumerated at all mesial interdental sites of the first permanent molars with aid of a modified chairside technique. The patients were then treated three times within 2 weeks with either a 1% CHX/thymol-containing varnish (group A) or a 1% CHX gel (group B), or they were subjected to daily supervised toothbrushing with a 0.4% CHX dentifrice for 1 month (group C). Follow-up samples of saliva and plaque from the interdental sites were collected 1 and 3 months after termination of treatment. A statistically significant reduction of MS levels in saliva and interdental plaque was found in all groups after 1 month. The CHX-containing dentifrice (group C) was the most effective method in reducing MS levels in saliva, and a significantly stronger (p < 0.05) suppression was found after 1 and 3 months when compared with the gel and the varnish forms. The ge...Continue Reading

Citations

Apr 28, 2000·Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopädie : Organ/official Journal Deutsche Gesellschaft Für Kieferorthopädie·I GehlenC Katsaros
Nov 1, 2001·Clinical and Diagnostic Laboratory Immunology·Y ShimazakiT Koga
Feb 27, 2008·The Angle Orthodontist·Ekaterini PaschosIngrid Rudzki-Janson
Apr 14, 2015·The Cochrane Database of Systematic Reviews·Tanya WalshDeborah Moore
Sep 15, 2000·The Journal of the American Dental Association·A I Ismail, J D Bader

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