Abstract
The study was performed to assess potential differences in the etiological relevance of two coagulase-negative staphylococci (CoNS), Staphylococcus haemolyticus and Staphylococcus hominis, in an observational single-center study. Over a 5-year interval, patients in whom there was detected S. haemolyticus or S. hominis of presumed etiological relevance were assessed for the primary endpoint death during hospital stay and the secondary endpoint transfer to an intensive care unit (ICU) after the detection of S. haemolyticus or S. hominis. Patients with S. haemolyticus or S. hominis died in 11.3% (50 out of 444) and 9.5% (60 out of 631) of cases, respectively, and were transferred to ICU after S. haemolyticus and S. hominis detection in 8.7% (19 out of 219) and 11.7% (44 out of 377) of cases, respectively. There was no significance for species-related influence on the primary outcome parameter (P > 0.1), while ICU transfers were more likely for patients with S. hominis detections (P = 0.016). Delayed diagnosis of both CoNS species was associated with an increased probability of death (P = 0.009). The study revealed comparable morbidity caused by S. haemolyticus and S. hominis identified in a clinically relevant context.
References
Jul 1, 1990·Infection and Immunity·M LoyerJ G Bisaillon
Jan 4, 2001·The American Journal of Medicine·S K SeoM H Samore
Nov 1, 2002·The Lancet Infectious Diseases·Christof von EiffChristine Heilmann
Oct 22, 2003·BMC Medical Research Methodology·Aluísio J D Barros, Vânia N Hirakata
Sep 8, 2005·Journal of Clinical Microbiology·Fernando ChavesJoaquín R Otero
Oct 21, 2005·Journal of Bacteriology·Fumihiko TakeuchiKeiichi Hiramatsu
May 18, 2006·The International Journal of Artificial Organs·C von EiffD Campoccia
May 18, 2006·The International Journal of Artificial Organs·C R ArciolaL Montanaro
Oct 17, 2006·Clinical Microbiology Reviews·Keri K Hall, Jason A Lyman
Sep 12, 2007·Heart & Lung : the Journal of Critical Care·Burke A CunhaMelissa Larusso
May 27, 2008·Genome Research·Elizabeth A GriceJulia A Segre
Sep 9, 2008·The Journal of Antimicrobial Chemotherapy·Izabel Cristina Vanzato PalazzoAna Lúcia da Costa Darini
Jul 16, 2011·PloS One·Ons BouchamiMaria Miragaia
Oct 20, 2012·The Pediatric Infectious Disease Journal·Hiie SoeorgIrja Lutsar
Sep 17, 2013·Memórias do Instituto Oswaldo Cruz·Patricia Vollú SilvaLenise Arneiro Teixeira
Jul 6, 2014·Folia Microbiologica·Ewa SzczukaAdam Kaznowski
Oct 4, 2014·Clinical Microbiology Reviews·Karsten BeckerGeorg Peters
Apr 30, 2015·Environmental Microbiology·Ursula KasparKarsten Becker
Dec 29, 2015·Annals of Laboratory Medicine·Sung Jin JoYeon-Joon Park
Apr 28, 2016·The Journal of Antimicrobial Chemotherapy·Ariane DeplanoOlivier Denis
May 27, 2016·Journal of Clinical Microbiology·Chun-Fu YehJang-Jih Lu
Sep 11, 2016·Journal of Microbiological Methods·Silvia Angeletti
Sep 24, 2016·Infection·Florian HitzenbichlerFrank Hanses
May 27, 2017·BMC Microbiology·Ali KassimGunturu Revathi
Jun 10, 2017·Frontiers in Cellular and Infection Microbiology·Fei DaMichael Otto
Mar 8, 2018·Revista Da Sociedade Brasileira De Medicina Tropical·Lucas Eduardo TrevisoliLibera Maria Dalla-Costa
Citations
Jan 30, 2020·BMC Microbiology·Yuanqing LuTengfei Zhang
Feb 13, 2020·BMC Infectious Diseases·Magdalena SzemrajEligia M Szewczyk
Feb 27, 2020·International Journal of Pediatrics·Brett WalkerWalid K Yassir
Jan 5, 2021·Current Microbiology·Maria Juviann IsaacsCathrine Sumathi Manohar