Comparison of the healing process in plated and non-plated fractures of the mandible in rats

The British Journal of Oral & Maxillofacial Surgery
L RasubalaM Ohishi

Abstract

We compared the healing process of plated and non-plated fractures. The mandibles of 72 male Wistar rats were fractured and more either plated or not plated (n = 36 in each group). The healing process of the two conditions was studied histologically and immunohistochemically using a specific antibody to bone morphogenetic protein-2 (BMP-2). The results showed that the healing process in the plated group was delayed by one week compared with the non-plated group. Trauma to the surrounding soft tissues affected the healing process. BMP-2 was expressed at all stages in both groups. We conclude that the healing process is disturbed by the fixing of a plate; that periosteum is one of the main sources of osteogenic cells; and that BMP-2 is an important regulator of morphogenesis.

References

Jun 1, 1987·Acta Orthopaedica Scandinavica·A HenricsonO Johnell
Nov 1, 1985·Clinical Orthopaedics and Related Research·M A Nathanson
Nov 12, 1965·Science·M R Urist
Oct 1, 1980·Arthritis and Rheumatism·M Owen
Aug 1, 1982·Acta Orthopaedica Scandinavica·A MølsterG Bang
Jun 1, 1993·Acta Orthopaedica Scandinavica·O Grundnes, O Reikerås
Mar 3, 1999·Journal of Orthopaedic Trauma·S H ParkA Sarmiento
Jul 5, 2001·The British Journal of Oral & Maxillofacial Surgery·T SuzukiT Nojima
Apr 4, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Shuying YangRenny T Franceschi
Jun 14, 2003·The British Journal of Oral & Maxillofacial Surgery·L RasubalaM Ohishi

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Citations

May 24, 2005·The British Journal of Oral & Maxillofacial Surgery·A A Shahidul IslamM Ohishi
Aug 12, 2008·Archives of Oral Biology·Renato M MendesAnderson J Ferreira
Mar 14, 2008·International Journal of Experimental Pathology·Cássio Edvard SverzutPaulo Tambasco de Oliveira
Sep 11, 2010·Critical Reviews in Food Science and Nutrition·M GobbettiM De Angelis
Oct 31, 2020·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Eric J Murnan, Brian J Christensen

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