PMID: 9664273Jul 17, 1998Paper

Comparison of the homogeneity of breast dose distributions with and without the medial wedge

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
C L IknerR J Lee

Abstract

Radiation of the intact breast often requires medial and lateral wedges to improve dose homogeneity of its pyramidal shape and to achieve acceptable cosmesis. There is some concern that radiation scatter from the medial wedge may contribute to cancer in the uninvolved breast, yet treatment without the medial wedge is associated with inhomogeneity of magnitudes that affect cosmesis. These homogeneities are identified on treatment plans generated at the central axis (CAX). It is not known if comparing isodose curves at the central axis reflect homogeneity in superior and inferior planes. A study was undertaken to both examine inhomogeneity with and without the medial wedge, and to determine if plan selection at the CAX was representative of homogeneity above and below the CAX. Ten consecutive patients with early breast cancers had cranial, CAX, and caudal CT images of each breast compared with two wedging conditions, lateral only (LW) and medial and lateral wedged conditions (dual wedges = DW). Dosimetry was optimized at the CAX for DW and LW conditions. Dose distributions and hot spots relative to prescribed dose were compared for cranial, CAX, and caudal images. Mean chest wall separations were measured. Six of ten patients had...Continue Reading

References

Mar 29, 1992·The New England Journal of Medicine·J D BoiceJ T Flannery
May 15, 1991·International Journal of Radiation Oncology, Biology, Physics·L J SolinJ M Manolis
Dec 1, 1989·International Journal of Radiation Oncology, Biology, Physics·L M ChinJ R Harris
Aug 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J M KurtzJ M Spitalier
Mar 1, 1985·International Journal of Radiation Oncology, Biology, Physics·B A FraassA S Lichter
Nov 30, 1995·The New England Journal of Medicine·UNKNOWN Early Breast Cancer Trialists' Collaborative Group
Feb 1, 1996·International Journal of Radiation Oncology, Biology, Physics·C A KellyW F Hartsell
Jul 1, 1997·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·I J DasB Fowble
Aug 1, 1997·International Journal of Radiation Oncology, Biology, Physics·T A BuchholzB R Prestidge

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Citations

Feb 25, 2005·Australasian Radiology·R DrummondA Rodger
Dec 1, 2006·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Carmen C PopescuWayne A Beckham
Aug 31, 2006·The British Journal of Radiology·K VenablesP J Hoskin
Mar 23, 2007·Technology in Cancer Research & Treatment·R PrabhakarS Thulkar
Oct 25, 2001·Journal of Applied Clinical Medical Physics·W A ToméB P Paliwal

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