PMID: 8582142Aug 1, 1995Paper

Comparison of the in vitro activity of levofloxacin and other antimicrobial agents against vancomycin-susceptible and vancomycin-resistant Enterococcus species

Diagnostic Microbiology and Infectious Disease
M K HaydenG M Trenholme

Abstract

The in vitro activities of levofloxacin and other antibiotics against 133 clinical isolates of vancomycin-resistant and vancomycin-susceptible enterococci were evaluated. Only 14 (39%) of the vancomycin-susceptible isolates and 11 (11%) of the vancomycin-resistant isolates were susceptible to levofloxacin. Levofloxacin exhibited a marked inoculum effect for all enterococci tested. These results suggest that levofloxacin may be of limited use in the treatment of serious enterococcal infections.

References

Nov 1, 1992·Antimicrobial Agents and Chemotherapy·D R SchabergC A Kauffman
Jan 1, 1989·Antimicrobial Agents and Chemotherapy·D F Sahm, G T Koburov
Jan 1, 1988·The Journal of Antimicrobial Chemotherapy·M J ZervosC A Kauffman
Mar 1, 1987·Antimicrobial Agents and Chemotherapy·M Fernandez-GuerreroW R Wilson
Jul 1, 1994·Antimicrobial Agents and Chemotherapy·S BurneyJ M Quale
Aug 1, 1993·Diagnostic Microbiology and Infectious Disease·M B PerriM J Zervos
Nov 1, 1993·Antimicrobial Agents and Chemotherapy·N C ClarkF C Tenover
May 1, 1993·Antimicrobial Agents and Chemotherapy·M VendittiP Martino

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Citations

Jan 5, 2001·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·J ManzellaD Pope
Apr 9, 1998·The Annals of Pharmacotherapy·S J MartinS L Pendland
Jun 1, 2014·The Journal of Antimicrobial Chemotherapy·Stije J LeopoldConstance Schultsz

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