PMID: 8950566Oct 1, 1996Paper

Comparison of the indirect immunofluorescent antibody test and the direct agglutination test for serodiagnosis of visceral leishmaniasis in HIV-infected subjects

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
L NigroR Russo

Abstract

One hundred subjects positive for anti-human immunodeficiency virus (HIV) antibodies were tested for anti-Leishmania antibodies by the indirect immunofluorescent antibody test (IFAT) and the direct agglutination test (DAT). Subjects were subsequently followed for two years to monitor the onset of visceral leishmaniasis. Fifteen subjects were positive for anti-Leishmania antibodies in either one or both tests. Eleven were positive only by IFAT, one only by DAT, and three by both tests. During the two-year follow-up period, nine subjects developed visceral leishmaniasis; of these, six were serologically positive, four by IFAT alone and two by both tests. The results indicate that IFAT and DAT have a similar specificity but that IFAT has a higher sensitivity and a greater diagnostic significance.

References

May 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·S H el Safi, D A Evans
Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·A E HarithJ J Laarman
Mar 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·E RosenthalF Gambarelli
May 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·N SinglaV K Vinayak
Jul 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·E A Okong'o-OderaA Kharazmi
Jan 1, 1994·Parasitology Today·J Alvar

❮ Previous
Next ❯

Citations

Dec 29, 1998·International Journal of Dermatology·R Marsella, R Ruiz de Gopegui
Jan 26, 2010·PLoS Neglected Tropical Diseases·Gustavo A S Romero, Marleen Boelaert
Aug 19, 2018·Parasite Immunology·Claudia AbeijonAntonio Campos-Neto
Apr 27, 2019·BMC Cancer·Biniyam Tefera DeressaDaniel Rauch
Mar 12, 2020·Frontiers in Cellular and Infection Microbiology·Maude F LévêqueChristelle Pomares

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.