Comparison of the international normalized ratio levels obtained by portable coagulometer and laboratory in a clinic specializing in oral anticoagulation

International Journal of Laboratory Hematology
Z M MenegheloA P Cora

Abstract

Therapy with Vitamin K antagonists (VKA) is effective in reducing thromboembolic events in various diseases. There are limitations however, which limit clinical handling and maintaining INR within therapeutic range. Studies have shown that portable coagulometers, when compared to laboratory tests, are more practical and provide better patient adherence and involvement toward treatment which results in better INR control. This study aimed to evaluate laboratory obtained INR results compared to two different portable coagulometers. A prospective study which monitored 1009 patients using VKA in the Anticoagulation Clinic at the Institute Dante Pazzanese of Cardiology in São Paulo between July and September 2012. Patient INR values were obtained by the laboratory through venipuncture and then compared to INR values obtained by capillary puncture from two different portable coagulometers. Overall, 1009 patients were included in the study; among these, 520 (51.5%) are male with average age of 59.6 years (13-91). The more common indications were atrial fibrillation (49.9%) and mechanical prosthesis (33.7%). The correlation coefficient was of 0.95 with and 0.88 with INRatio PT Monitor(®) compared to laboratory. In patients with INR < 2...Continue Reading

References

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Citations

Sep 19, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Antonio E Jerez CaleroJosé Uberos Fernández
Apr 6, 2017·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Sara R VazquezStacy A Johnson
Jun 4, 2020·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Silmara Aparecida de Lima MontalvãoJoyce Maria Annichinno-Bizzachi
Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Heta Jigar PanchalLeanne F Harris

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