PMID: 16532610Mar 15, 2006Paper

Comparison of the linear finite element prediction of deformation and strain of human cancellous bone to 3D digital volume correlation measurements

Journal of Biomechanical Engineering
R ZauelD P Fyhrie

Abstract

The mechanical properties of cancellous bone and the biological response of the tissue to mechanical loading are related to deformation and strain in the trabeculae during function. Due to the small size of trabeculae, their motion is difficult to measure. To avoid the need to measure trabecular motions during loading the finite element method has been used to estimate trabecular level mechanical deformation. This analytical approach has been empirically successful in that the analytical models are solvable and their results correlate with the macroscopically measured stiffness and strength of bones. The present work is a direct comparison of finite element predictions to measurements of the deformation and strain at near trabecular level. Using the method of digital volume correlation, we measured the deformation and calculated the strain at a resolution approaching the trabecular level for cancellous bone specimens loaded in uniaxial compression. Smoothed results from linearly elastic finite element models of the same mechanical tests were correlated to the empirical three-dimensional (3D) deformation in the direction of loading with a coefficient of determination as high as 97% and a slope of the prediction near one. However...Continue Reading

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Citations

Dec 21, 2010·Computer Methods in Biomechanics and Biomedical Engineering·S E BaslerG H van Lenthe
May 20, 2009·Journal of Biomechanical Engineering·Michael R Hardisty, Cari M Whyne
Feb 1, 2013·Journal of Biomechanical Engineering·M R HardistyD P Fyhrie
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Nov 30, 2019·The Review of Scientific Instruments·Bartosz PowierzaGiovanni Bruno

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