PMID: 43517Nov 1, 1979

Comparison of the long-term cumulative effects of reserpine and syrosingopine on general activity

Pharmacology, Biochemistry, and Behavior
T Palfai, T J Walsh


Reserpine, but not syrosingopine, produced a cumulative decrease in general motor activity when administered once every 10 days for a total of 8 drug treatments. The maximum depression of activity was evident following the second reserpine administration. Following a 30 day drug-free period animals previously treated with reserpine still exhibited decreased motor activity. The data suggest that chronic reserpine treatment may result in long term, and perhaps permanent behavioral effects.


Feb 1, 1978·Pharmacology, Biochemistry, and Behavior·T J Walsh, T Palfai
Jan 1, 1975·Naunyn-Schmiedeberg's Archives of Pharmacology·A Giachetti, P A Shore
Jun 1, 1969·Biochemical Pharmacology·H S Alpers, P A Shore
Sep 1, 1967·International Journal of Neuropharmacology·J H PirchK E Moore
Jan 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·C MAGGIOLO, T J HALEY

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