Comparison of the mitral valve morphologies of Cavalier King Charles Spaniels and dogs of other breeds using 3D transthoracic echocardiography

Journal of Veterinary Internal Medicine
Giulio MenciottiJonathan A Abbott

Abstract

Myxomatous mitral valve disease (MMVD) is more prevalent in Cavalier King Charles Spaniels (CKCSs) compared to dogs of other breeds at a given age. Abnormal valvular stress is thought to contribute to the development and progression of MMVD, and a relationship exists between mitral valve (MV) morphology and stress acting on the valve. To determine whether the MV morphology of healthy adult CKCSs differs from the morphology of healthy adult dogs of other breeds determined by RT-3DTTE. Thirty-five healthy CKCSs and 41 healthy dogs of other breeds. Prospective cross-sectional study. Dogs underwent physical examination, conventional echocardiography, and RT-3DTTE. RT-3DTTE datasets were analyzed using dedicated software for MV morphologic analysis. Morphologic variables were compared between CKCSs and dogs of other breeds. The MV of healthy CKCSs had a smaller annulus height (0.46 ± 0.11 vs. 0.56 ± 0.17; P = .0021), tenting height (0.26 ± 0.12 vs. 0.42 ± 0.18; P < .001), tenting area (0.42 ± 0.15 vs. 0.79 ± 0.34; P < .001), normalized tenting volume (0.09 [0.05-0.13] vs. 0.14 [0.10-0.20]; P < .001), and normalized area of the posterior leaflet (0.57 ± 0.15 vs. 0.66 ± 0.18; P = .016) compared to healthy dogs of other breeds; this re...Continue Reading

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Citations

Apr 1, 2019·Veterinary World·Yury A VatnikovAndrey N Zharov
Aug 23, 2020·Animals : an Open Access Journal From MDPI·Mara BagardiPaola Giuseppina Brambilla
Jan 17, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Brian A Scansen, Randi Drees
Jan 17, 2020·Journal of Veterinary Internal Medicine·Brian A Scansen, Randi Drees
Oct 11, 2020·Current Cardiology Reports·B N HorowitzAnnika Linde
Dec 29, 2020·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·S SudunaguntaJ Dukes-McEwan
May 25, 2021·Animal Genetics·M J O'BrienC M Wade

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Software Mentioned

TomTec
RT
3DTTE
JMP Pro
4D MV Analysis

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