Comparison of the multichannel intraluminal impedance pH and conventional pH for measuring esophageal acid exposure: a propensity score-matched analysis

Surgical Endoscopy
Masato HoshinoKatsuhiko Yanaga

Abstract

The modalities for evaluating acid reflux in medical care for gastroesophageal reflux disease (GERD) include conventional pH (C-pH), wireless pH (Bravo®) and multichannel intraluminal impedance pH (MII-pH), which have been reported to vary with respect to the duration of acid reflux. In this study, we examined the difference between the acid reflux in C-pH and MII-pH among patients with GERD. Prior to initial laparoscopic fundoplication carried out on 297 cases from December 1994 to April 2016, an upper gastrointestinal endoscopy and C-pH or MII-pH were conducted. A propensity score-matched analysis was carried out about five factors including age, sex, BMI, the extent of reflux esophagitis (Los Angeles classification), and the presence of hiatal hernia (HH), ultimately leading to the creation of a C-pH group (81 cases) and MII-pH group (81 cases) as the subjects. Concerning pH < 4 holding time (18.9 vs. 7.3%, p < 0.001), DeMeester score (58.5 vs. 24.4, p < 0.001), and the number of times reflux continued for longer than 5 min (8.8 vs. 4.1 times/day, p = 0.002), the C-pH group had significantly higher values for each, while the positive rate of acid reflux (Positive pH) was significantly higher in the C-pH group (p < 0.001), at...Continue Reading

References

Jun 30, 2005·The American Journal of Gastroenterology·John E PandolfinoPeter J Kahrilas
Oct 8, 2005·Scandinavian Journal of Gastroenterology·Ikuyo MishimaYoshikazu Kinoshita
Mar 25, 2006·Alimentary Pharmacology & Therapeutics·S EmerenzianiM Cicala
Feb 14, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Amine HilaDonald O Castell
Apr 19, 2007·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J L Wise, J A Murray
Dec 4, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Reginald V N LordTom R DeMeester
Feb 28, 2015·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·E J NdebiaJ E Iputo

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Citations

Dec 19, 2018·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R M L NetoM G Patti

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