Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys

Allergy
G LiljaS Bevegård

Abstract

Fourteen boys with a mean age of 12.2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG). All had a positive history of EIA and a post-exercise fall in FEV1 of more than 20%. A double blind cross-over technique was used with a 1 week wash-out period between the two treatment alternatives. Both drugs gave some, but not significant protection for EIA and no differences between the two active substances tested were found. Great individual differences in the response to the two drugs were noted.

References

Dec 1, 1979·The Journal of Allergy and Clinical Immunology·S AndersonD A Lindsay
May 1, 1978·Clinical Allergy·R PauwelsM Van Der Straeten
Jun 1, 1972·Archives of Disease in Childhood·M Silverman, T Andrea
Apr 1, 1981·Thorax·I S PetheramS G Spiro

❮ Previous
Next ❯

Citations

Jan 25, 2002·Archives of Disease in Childhood·A Baki, F Orhan
Jul 1, 1987·British Journal of Clinical Pharmacology·P RaffertyI W Grant
Aug 1, 1989·The Journal of Allergy and Clinical Immunology·P Rafferty, S T Holgate
Mar 1, 1986·Clinical Allergy·U BrobergerE Rylander

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.