Comparison of the Short-Term and Long-Term Effects of Surgery and Nonsurgical Intervention in Treating Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis.

Hand : Official Journal of the American Association for Hand Surgery
Qiyun ShiJoy C MacDermid

Abstract

Background: The objective of the study is to examine the short-term and long-term efficacy of surgical treatment of carpal tunnel syndrome (CTS) compared with conservative treatment (ie, splint, steroid injection, or physical therapy). Methods: Two reviewers searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and PEDro up to September 2017. Quality appraisal and data extraction were performed in duplicate. Patient self-reported functional and symptom changes, as well as improvement of electrophysiological studies, were assessed as outcomes. Meta-analyses were performed in RevMan. Results: From 1438 studies identified after searching, 10 remained for analysis after exclusion criteria were applied. Moderate-quality evidence indicated that surgical interventions were superior to splint or steroid injection at 6 months with a weighted mean difference of 0.25 (95% confidence interval [CI], 0.07-0.44) for functional status and 0.64 (95% CI, 0.07-1.21) for symptom severity. The surgical group had better nerve conduction outcomes at 6 months (0.57 [95% CI, 0.05-0.50] ms). No significant differences were observed at 3 or 12 months. Conclusions: Both surgical and conservative interventions provide treatment bene...Continue Reading

References

Nov 1, 1986·The Journal of Bone and Joint Surgery. British Volume·D J Ford, M S Ali
Feb 1, 1996·Controlled Clinical Trials·A R JadadH J McQuay
Apr 6, 1999·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·M E Boeckstyns, A I Sørensen
Sep 7, 2002·JAMA : the Journal of the American Medical Association·Annette A M GerritsenLex M Bouter
Oct 24, 2006·BMC Musculoskeletal Disorders·Jose C de Carvalho LeiteFujian Song
Apr 12, 2011·Journal of Orthopaedic Surgery and Research·Qiyun Shi, Joy C MacDermid
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Sep 2, 2014·Archives of Physical Medicine and Rehabilitation·Matthew S ThieseDavid Rempel
Aug 19, 2015·The Journal of Pain : Official Journal of the American Pain Society·César Fernández-de-Las PeñasMaria L Cuadrado-Pérez
Dec 15, 2015·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Guner Celik, Mustafa Kemal Ilik

❮ Previous
Next ❯

Citations

May 3, 2019·Pain Practice : the Official Journal of World Institute of Pain·César Fernández-de-Las-PeñasDeborah Falla
May 3, 2019·Muscle & Nerve·Gary M Franklin, Bradley Evanoff
Jul 1, 2020·F1000Research·César Fernández-de-Las-PeñasAna I De-la-Llave-Rincón
Aug 9, 2020·Physical Therapy·César Fernández-de-Las-PeñasRicardo Ortega-Santiago
Mar 7, 2021·International Journal of Environmental Research and Public Health·Valentina ScaliseFrancesca Bonetti
May 28, 2021·BMC Musculoskeletal Disorders·Juhani MultanenJari Ylinen
Aug 4, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Bernard X W LiewCésar Fernández-de-Las-Peñas
Dec 4, 2021·Archives of Physical Medicine and Rehabilitation·Rodrigo Núñez-CortésSofía Pérez-Alenda

❮ Previous
Next ❯

Software Mentioned

Review Manager ( RevMan )
PRISMA
PEDro

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.