Comparison of the TaqMan and LightCycler systems in pharmacogenetic testing: evaluation of CYP2C9*2/*3 polymorphisms

Clinical Chemistry and Laboratory Medicine : CCLM
Mario TorielloLucia Sacchetti

Abstract

Pharmacogenetic testing for drug-metabolizing enzymes is not yet widely used in clinical practice. In an attempt to facilitate the application of this procedure, we have compared two real-time PCR-based methods, the TaqMan and the LightCycler for the pharmacogenetic evaluation of CYP2C9*2/*3 polymorphisms. Both procedures are suitable for pharmacogenetic studies. The TaqMan procedure was less expensive in terms of cost per sample, but the TaqMan apparatus is more expensive than the LightCycler apparatus.

References

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Citations

Jul 11, 2013·Molecular Diagnosis & Therapy·Sherif M M EkladiousHazem S Abou-Youssef
Jan 2, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Sheng-Wen HuangXiang-Min Xu

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Methods Mentioned

BETA
genotyping
PCR

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