PMID: 11326703May 1, 2001Paper

Comparison of the test methods (KRYPTOR, ES 600 and CIS-RIA) for CEA, CA 15-3 and CA 125 follow-up and ONCOCHECK-quality control

Anticancer Research
T BauerG Sturm

Abstract

We examined whether the automated KRYPTOR/CIS analysis system could replace the routine tumor marker tests. We analysed the sera of 50 patients by EnzymImmunoAssay CEA (ES-600, Roche/Boehringer), CA 15-3 (ELSA/RIA; CIS) CA 125 (Centocor/RIA; CIS) and in parallel by KRYPTOR (CIS). The correlation coefficient for CEA and CA 125 was clearly less than that of Centocor. Although the automated KRYPTOR is suitable for routine analysis a larger number of patients sera must be tested by different methods, especially in view of the lack of international reference material, before completely switching over to KRYPTOR.

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