Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis

Arthritis Care & Research
Raquel Campanilho-MarquesJuvenile Dermatomyositis Research Group

Abstract

To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10-cm skin visual analog scale (VAS) in order to define which tool best assesses skin disease in patients with juvenile dermatomyositis. A total of 71 patients recruited to the UK Juvenile Dermatomyositis Cohort and Biomarker Study were included and assessed for skin disease using the CAT, DAS, MITAX, and skin VAS. The Childhood Myositis Assessment Scale (CMAS), manual muscle testing of 8 groups (MMT8), muscle enzymes, inflammatory markers, and physician's global VAS were recorded. Relationships were evaluated using Spearman's correlations and predictors with linear regression. Interrater reliability was assessed using intraclass correlation coefficients. All 3 tools showed correlation with the physician's global VAS and skin VAS, with DAS skin showing the strongest correlation with skin VAS. DAS skin and CAT activity were inversely correlated with CMAS and MMT8, but these correlations were moderate. No correlations were found between the skin tools and inflammatory markers or muscle enzymes. DAS skin and CAT were the quickest to complete (mean ±...Continue Reading

References

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Jan 31, 2006·Journal of the American Academy of Dermatology·Jennifer L HundleyJoseph L Jorizzo
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Oct 27, 2009·Best Practice & Research. Clinical Rheumatology·Lucy R Wedderburn, Lisa G Rider

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Citations

Feb 21, 2018·Statistics in Medicine·Maria De IorioLucy Wedderburn
Apr 11, 2018·Current Rheumatology Reports·Silvia RosinaAngelo Ravelli
Aug 21, 2018·Current Opinion in Rheumatology·Giulia C VarnierLucy R Wedderburn
Feb 5, 2019·Brain : a Journal of Neurology·Charalampia PapadopoulouDespina Eleftheriou
Mar 9, 2021·Current Rheumatology Reports·Gabriella GiancaneNicolino Ruperto
Apr 27, 2021·Best Practice & Research. Clinical Rheumatology·Ivan Foeldvari, Kathryn S Torok

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Methods Mentioned

BETA
ESR

Software Mentioned

MITAX
CAT

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