Comparison of two different injection rates of gadoxetic acid for arterial phase MRI of the liver

Journal of Magnetic Resonance Imaging : JMRI
Sang-Hoon ChungHye-Suk Hong

Abstract

To compare two different injection rates for gadoxetic acid-enhanced hepatic arterial phase images on hepatic dynamic MRI. Hepatic arterial phase images were obtained after an intravenous bolus injection of gadoxetic acid at a rate of 1 mL/second in 62 patients and 2 mL/second in 64 patients on a 3 Tesla MR scanner using a test-bolus injection method. The signal-to-noise ratios (SNR) of the liver, portal vein, hepatic vein, aorta, spleen and pancreas were measured. The contrast-to-noise ratio (CNR) of hypervascular hepatic tumors was calculated. Two radiologists independently scored items to evaluate image quality of hepatic arterial phase and detected hypervascular hepatocellular carcinoma (HCC). The SNR of the aorta on the arterial phase images was significantly higher in the 1 mL/second group (235.43 +/- 82.59) than in the 2 mL/second group (190.94 +/- 96.90, P < 0.05). The SNRs of the liver, spleen and pancreas, the CNRs of hypervascular hepatic tumors, the detection rate of hypervascular HCC and subjective ratings for the optimal arterial enhancement were comparable between the two groups. Injection rates of 2 mL/second and 1 mL/second provided comparable image qualities on arterial phase images of hepatic dynamic MRI usin...Continue Reading

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Citations

May 10, 2011·Pediatric Radiology·Anobel Tamrazi, Shreyas S Vasanawala
Sep 26, 2013·AJR. American Journal of Roentgenology·Hyeon Tae JeongKi Whang Kim
Jun 26, 2013·AJR. American Journal of Roentgenology·Christoph J ZechClaude B Sirlin
Jan 10, 2012·Magnetic Resonance Imaging·Shigehiro MorikawaToshiro Inubushi
Apr 9, 2013·NMR in Biomedicine·Jose L UlloaPaul D Hockings
Dec 1, 2012·Journal of Magnetic Resonance Imaging : JMRI·Mukta D AgrawalMartin R Prince
Feb 2, 2013·Journal of Magnetic Resonance Imaging : JMRI·Thomas A HopeShreyas S Vasanawala
May 23, 2015·AJR. American Journal of Roentgenology·So Yeon KimBenjamin M Yeh
Aug 2, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Toshimasa J ClarkJeffrey H Maki
Sep 9, 2017·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Xijiao LiuBin Song
Nov 18, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jimi HuhWei Chou Chang
Sep 24, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sung Mo KimHeoung Keun Kang
Oct 2, 2012·Acta Radiologica·Christine Schmid-TannwaldChristoph Zech

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