PMID: 8447713Mar 22, 1993Paper

Comparison of two noninvasive screening tests for renovascular hypertension

Archives of Internal Medicine
W J ElliottM B Murphy

Abstract

To compare and contrast the diagnostic accuracy rates of two newer noninvasive screening tests for renovascular hypertension, the most common curable cause of secondary hypertension. One hundred fifty patients, thought to have a high probability of renovascular hypertension by established clinical criteria, underwent both the captopril challenge test and the renal scintigram with angiotensin-converting enzyme inhibitor, while on their usual antihypertensive regimen except angiotensin-converting enzyme inhibitors. If the result of either test was abnormal, angiography was undertaken, followed immediately by angioplasty (if a stenosis was found) or by renal vein renin determinations. Patients whose blood pressures were lower 6 to 12 weeks after a revascularization procedure (surgery or angioplasty) were diagnosed as having renovascular hypertension. Of the 150 patients, 100 underwent angiography, and 59 had renal artery stenosis. Of 53 patients who had surgery (n = 21) or angioplasty (n = 32), 51 had lowered blood pressures compared with before the procedure. Sensitivity and specificity of the tests were as follows: renal scintigram with angiotensin-converting enzyme inhibitor: 92% and 91% (all patients) and 92% and 80% (only pat...Continue Reading

Citations

Sep 19, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·S D Sarkar, D N Siegel
Jun 22, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·I KrenzR A Stahl
Feb 15, 2000·Journal of Internal Medicine·K H HelinI Tikkanen
Nov 1, 2005·Current Cardiology Reports·Martin Senitko, Andrew Z Fenves
Sep 25, 2010·American Journal of Hypertension·Stephen C Textor, Lilach Lerman
Dec 19, 2006·Critical Reviews in Clinical Laboratory Sciences·Gian Paolo RossiAchille C Pessina

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