Comparison of vectorcardiographic and 12-lead electrocardiographic detections of abnormalities in repolarization properties due to preexcitation in patients with Wolff-Parkinson-White syndrome: proposal of a novel concept of a "remodeling gradient"

Japanese Heart Journal
M SuginoH Saito


Repolarization abnormalities after radiofrequency ablation in patients with manifest Wolff-Parkinson-White syndrome (WPW) have been attributed to cardiac memory of pre-existing changes in repolarization properties. We compared spatial ventricular gradient (VG) from vectorcardiograms with QRST values of 12-lead ECG in 41 patients with WPW (group A, manifest WPW due to left-sided accessory pathway (n = 20); group B, manifest WPW due to right-sided accessory pathway (n = 12); group C, concealed WPW (n = 9)) before and after ablation. Group N (n = 607) served as control. In groups A and B, the abnormalities of spatial VG and QRST values of 12-lead ECG that existed before and 1 day after ablation significantly decreased 1 week after ablation. In group C, spatial VG and QRST values of 12-lead ECG showed no significant changes. The diagnostic ability of spatial VG is almost equivalent to that of the QRST value of ECG in detecting repolarization abnormalities in patients with WPW before and after ablation. We propose a new concept of a "remodeling gradient" directing from the preexcited area to the opposite side of the ventricle as a result of preexcitation-induced electrical remodeling.


Oct 1, 1979·Journal of Electrocardiology·R Plonsey
Sep 1, 1978·Circulation Research·H Toyoshima, M J Burgess
Dec 1, 1991·Journal of the American College of Cardiology·S J KalbfleischF Morady
Jan 1, 1988·Circulation Research·S H Litovsky, C Antzelevitch
Sep 1, 1970·Chest·J A AbildskovR Wyatt
Feb 1, 1971·American Heart Journal·J A AbildskovG Baule
Aug 1, 1982·The American Journal of Cardiology·M B RosenbaumJ M Davidenko
Aug 1, 1982·The American Journal of Cardiology·B Surawicz
Jul 1, 1981·Journal of Electrocardiology·P NicolaiA Pisapia
Jan 1, 1996·Physiological Reviews·K K DealM M Tamkun
Jan 1, 1996·Journal of Cardiovascular Electrophysiology·B Surawicz
Jan 1, 1996·Annual Review of Physiology·D M Barry, J M Nerbonne
Oct 1, 1996·Circulation·E G DaoudF Morady
Apr 1, 1997·Circulation·R G TielemanH J Crijns
Apr 29, 1998·Journal of Cardiovascular Electrophysiology·R GoyalF Morady
May 29, 1998·Circulation·A ShvilkinM R Rosen
Mar 23, 1999·Circulation·J A KorsJ H van Bemmel
Jun 4, 1999·Journal of Cardiovascular Electrophysiology·P RicardM R Rosen

❮ Previous
Next ❯


Sep 2, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Harmen H M DraismaCees A Swenne
May 21, 2015·Biomedizinische Technik. Biomedical Engineering·Muhammad A Hasan, Derek Abbott

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.