PMID: 2484510Jan 1, 1988Paper

Comparison of whole blood selenium values and erythrocyte glutathione peroxidase activities of normal individuals on supplementation with selenate, selenite, L-selenomethionine, and high selenium yeast

Biological Trace Element Research
J Clausen, S A Nielsen

Abstract

The selenium levels and the glutathione peroxidase activity GSH-PX of whole blood and of erythrocytes, respectively, were determined in 139 normal Danes and related to sex and smoking habits. No differences were found in relation to sex apart from a higher GSH-PX activity of females when assayed with tertiary butyl hydroperoxide. Smokers showed significantly lower selenium values than non-smokers (p less than 0.05), but the two groups had identical GSH-PX activities. Individuals from the above-mentioned group were divided into four groups, receiving daily oral doses of 200 micrograms of selenium in the form of selenite, selenate, L-selenomethionine, and selenium as contained in yeast. Whole blood selenium values and the erythrocyte glutathione peroxidase activities were determined during three months of supplementation followed by a withdrawal period of four months. Both the inorganic selenium compounds and the organic derivatives gave rise to steady state levels of GSH-PX after one month of supplementation. However, the selenium levels in the groups receiving organic selenium showed a steady rise during the whole period, whereas those supplemented with inorganic selenium leveled off after a period of one to three months. The d...Continue Reading

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Citations

Jan 1, 1997·Plant Foods for Human Nutrition·J LintschingerW Gössler
May 18, 1999·Biological Trace Element Research·Q LiuJ Clausen
Apr 21, 2005·Analytical and Bioanalytical Chemistry·Heidi Goenaga InfanteTim Catterick
Apr 4, 2015·Nutrients·Gerald F Combs
Apr 24, 2010·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Dietrich BehneAntonios Kyriakopoulos
Jul 1, 1992·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·M A Tariq, I L Preiss
May 1, 1992·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·M A Tariq, I L Preiss
Jul 6, 2014·Critical Reviews in Food Science and Nutrition·Ma Gorzata BodnarJacek Namieśnik
Feb 11, 2015·Applied Microbiology and Biotechnology·Chun-Lin Lee
Nov 4, 2004·The British Journal of Nutrition·Margaret P Rayman
Dec 1, 1993·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·R Sting, K Westphal
Nov 14, 2019·Hormones : International Journal of Endocrinology and Metabolism·Tomasz Bednarczuk, Lutz Schomburg
Sep 16, 2008·Journal of Animal Science·L CalamariG Bertin
Jun 16, 2006·Journal of Animal Science·S M RichardsonT L Ward
May 1, 1999·Alternatives to Laboratory Animals : ATLA·C M Frederiksen, J Clausen
Mar 25, 2018·Free Radical Biology & Medicine·Lucia A SealeMarla J Berry
Apr 17, 2021·Frontiers in Endocrinology·Blossom H PattersonMeryl E Wastney

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