Comparison study of different bowel preparation regimens and different fecal-tagging agents on tagging efficacy, patients' compliance, and diagnostic performance of computed tomographic colonography: preliminary study

Journal of Computer Assisted Tomography
Soon Ho YoonByung Ihn Choi


To compare and find the optimal combination of bowel preparation regimens and different concentrations of barium-based fecal-tagging agents on computed tomographic colonography in terms of tagging efficacy, patients' compliance, and diagnostic performance. Sixty-nine consecutive patients were prospectively enrolled and randomly divided into 4 groups according to a combination of bowel preparation regimens (sodium phosphate [Colclean] vs magnesium citrate [LoSoPrep]) and different concentrations of barium-based fecal-tagging agents (Tagitol V [thick, 40% wt/vol] 60 mL vs EasyCT [thin, 4.6% wt/vol] 600 mL). Patients who received Colclean and EasyCT were designated as group 1; Colclean and Tagitol V as group 2; LoSoPrep and EasyCT, group 3; and LoSoPrep and Tagitol V, group 4. For objective analysis, the volume of tagged feces and fluid was semiautomatically calculated using a threshold of 150 Hounsfield units. The volume of untagged feces and fluid was also calculated using the seeded region-growing method. The tagging efficacy was then calculated and compared using the analysis of variance test. For subjective analysis, 2 radiologists visually determined the overall tagging efficacy on a segmental basis. The numbers of homogeneo...Continue Reading


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