Comparisons among the diagnostic methods used for the detection of extra-pulmonary tuberculosis in Bangladesh

International Journal of Mycobacteriology
Saurab Kishore MunshiRashed Noor

Abstract

The present study was an attempt to establish a suitable method for the effective diagnosis of extra-pulmonary tuberculosis in Bangladesh. In this regard, detection of Mycobacterium tuberculosis from 390 different extra-pulmonary specimens was performed by Bright-Field microscopy, light-emitting diode fluorescence microscopy and Lowenstein-Jensen culture methods, followed by an extensive comparison among these methods. M. tuberculosis was detected in 53 cases through the conventional Lowenstein-Jensen culture method; 49 cases were detected under Bright-Field microscope, whereas the light-emitting diode fluorescence microscopy detected 64 cases. Out of 53 culture-positive isolates, 12 were found to be multi-drug resistant. Light-emitting diode fluorescence microscopy was found to be more sensitive and effective than both the Bright-Field microscopy and the Lowenstein-Jensen culture methods. Incidentally, light-emitting diode fluorescence microscopy appeared imperative to detecting the multi-drug resistant tuberculosis.

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Citations

Feb 12, 2013·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Rashed NoorS M Mostofa Kamal
Dec 1, 2013·International Journal of Mycobacteriology·Mehedi HasanRashed Noor
Jun 1, 2015·Ci Ji Yi Xue Za Zhi = Tzu-chi Medical Journal·Rashed Noor, Md Sakil Munna

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