PMID: 16636474Apr 26, 2006Paper

Comparisons of potentials for L-lysine production among different Corynebacterium glutamicum strains

Bioscience, Biotechnology, and Biochemistry
J Ohnishi, Masato Ikeda

Abstract

Corynebacterium glutamicum is an industrially important organism that is most widely used for the production of various amino acids. A defined L-lysine-producing mutant was generated by introduction of the lysC mutation (T311I) into each of six representative C. glutamicum strains. The resulting six isogenic mutants were compared for L-lysine production under traditional 30 degrees C conditions and industrially more advantageous 40 degrees C conditions. It was found that there were significant differences in yield and productivity, especially at 40 degrees C. These results indicate the diversity among C. glutamicum strains in fermentative characters, as well as the importance of selecting a strain with industrially best performance.

References

Jan 13, 2000·Trends in Biotechnology·A L Demain
Aug 1, 2002·International Journal of Systematic and Evolutionary Microbiology·Ryosuke FudouShigeru Yamanaka
Jan 14, 2003·Advances in Biochemical Engineering/biotechnology·Masato Ikeda
May 14, 2003·Applied Microbiology and Biotechnology·M Ikeda, S Nakagawa

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Citations

Jan 14, 2009·Applied and Environmental Microbiology·Masato IkedaMikiro Hayashi
Mar 24, 2007·Applied Microbiology and Biotechnology·Seiki TakenoMasato Ikeda
Dec 12, 2012·Omics : a Journal of Integrative Biology·Suma ChoorapoikayilDietmar Schomburg
Nov 1, 2015·Journal of Biotechnology·Pablo RavasiHugo G Menzella
Mar 21, 2007·Journal of Biotechnology·R TakorsK Huthmacher
Sep 24, 2019·Critical Reviews in Biotechnology·Fernanda Karine do Carmo FélixCarlos Ricardo Soccol
Apr 3, 2019·Journal of Industrial Microbiology & Biotechnology·Jian-Zhong XuWei-Guo Zhang

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