Abstract
To verify the utility of the 2-in-1-out-compartment model analysis (CMA) of intravenous contrast-enhanced dynamic computed tomography (IV-CT) for evaluating hepatic arterial and portal venous flow using intra-arterial contrast-enhanced CT (IA-CT). We retrospectively evaluated 49 consecutive patients who underwent IV-CT and were radiologically or histologically diagnosed as having hepatic malignant lesion (51 classical hepatocellular carcinomas [HCC], 4 early HCC, 3 cholangiolocellular carcinomas, 1 mixed HCC, 3 cholangiocellular carcinomas). As a gold standard for hepatic arterial and portal blood flows, we defined the normalized enhancement in CT values on CTAP (nCTAP) and CTHA (nCTHA). The hepatic arterial (k1a ) and portal venous inflow velocity (k1p ) constants in hepatic lesions and surrounding liver parenchyma were obtained from the CMA of IV-CT with various outflow velocity constant (k2 ) limits using the nonlinear least square method. The correlation coefficient between the normalized enhancement in IA-CT and CMA of IV-CT was statistically evaluated according to various k2 limits. The highest mean correlation coefficient between k1a and nCTHA (r = 0.65, P < 0.0001) was observed when k2 ≦0.035. The highest mean correlati...Continue Reading
References
Feb 1, 1991·Radiology·O MatsuiM Ida
Jan 10, 1998·Radiology·K UedaT Takashima
Dec 10, 1999·AJR. American Journal of Roentgenology·M HayashiY Nakanuma
Feb 27, 2001·AJR. American Journal of Roentgenology·B E Van BeersY Horsmans
Oct 2, 2002·Radiology·Makiko HayashiMasumi Kadoya
Jan 13, 2009·European Radiology·Tong San KohSotirios Bisdas
Mar 12, 2009·Radiology·Lorraine AshSuresh K Mukherji
May 5, 2009·Japanese Journal of Radiology·Masaya MiyazakiKeigo Endo
Jun 25, 2010·Radiology·Maxime RonotValérie Vilgrain
Dec 31, 2010·Japanese Journal of Radiology·Tomonori KandaKazuro Sugimura
Jan 27, 2011·Abdominal Imaging·Osamu MatsuiToshifumi Gabata
Aug 23, 2011·Radiological Physics and Technology·Shuichiro KobayashiKenya Murase
May 9, 2012·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jin Woong KimHeoung Keun Kang
May 25, 2012·Radiology·Steven SourbronChristoph J Zech
Sep 26, 2013·AJR. American Journal of Roentgenology·Bachir TaouliHenry Rusinek
Jul 25, 2014·Radiology·Se Hyung KimJürgen K Willmann
Apr 4, 2017·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Takeshi SuzukiMasumi Kadoya