Compartmentalized bone regeneration of cranial defects with biodegradable barriers: an animal model

The Journal of Craniofacial Surgery
Samuel StalLarry Hollier

Abstract

In bony defects of the cranium, bone healing may be complicated by prolapse of surrounding tissue into the defect. This tissue acts as an impediment to prevent the migration of osteogenic cells, leading to impaired bone formation. It has been previously shown that a membrane placed over the bony defect inhibits the connective tissue cells from entering the wound and theoretically improves bone formation. The use of a proven resorbable material, Lactosorb, is used in this animal model and has shown a significant increase in autogenous bony formation. The majority of previous work was accomplished with nonresorbable material that resulted in foreign body formation. This paper is unique because resorbable material in the animal model is relatively inexpensive and easy to use and has allowed successful autogenous bony regeneration.

References

Aug 1, 1992·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·D LundgrenB Klinge
Jan 1, 1990·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·C DahlinS Nyman
Nov 1, 1993·Journal of Biomedical Materials Research·S A AliD F Williams

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Citations

Mar 26, 2009·Acta Veterinaria Scandinavica·Péricles Nóbrega MendesFernanda da Cruz Landim-Alvarenga
Feb 4, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Neusa M F CostaJosé M Granjeiro
Apr 5, 2013·Journal of Biomedical Materials Research. Part a·Ashley MitchellJ Patrick O'Connor
Jun 29, 2004·Clinics in Plastic Surgery·Larry H Hollier, Samuel Stal
Nov 26, 2009·The Journal of Craniofacial Surgery·Daniel A Peters, Douglas J Courtemanche
Apr 4, 2006·Plastic and Reconstructive Surgery·Tony D FangMichael T Longaker
Mar 10, 2020·International Journal of Biomaterials·Carolina Ferrairo Danieletto-ZannaAna Paula Farnezi Bassi
Jun 16, 2012·Journal of Biomedical Materials Research. Part a·Marco A Alvarez PerezLuigi Ambrosio

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