Compartmentalizing Incompatible Tandem Reactions in Pickering Emulsions To Enable Visual Colorimetric Detection of Nitramine Explosives Using a Smartphone

Analytical Chemistry
Zhenyang XieYi He

Abstract

We report a visual colorimetric assay for detection of nitramine explosives such as 1,3,5-trinitro-1,3,5-triazinane (RDX) and 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) using a smartphone. This assay is based on compartmentalizing incompatible tandem reactions in Pickering emulsions. The alkaline hydrolysis of RDX or HMX in one Pickering emulsion produces nitrite ions, which autodiffuse into the other Pickering emulsion to form nitrous acid. It oxidizes the 3,3',5,5'-tetramethylbenzidine (TMB) to generate yellow TMB diimine. The RGB component change of the optical images is applied to quantitatively determine the RDX and HMX at different reaction temperatures. A distinct color change occurs at RDX and HMX concentrations of 1.2 and 12 μM, respectively. The adjusted intensity increases linearly with the increase of the logarithms of the concentrations of RDX and HMX in the range of 1.2-90 μM and 12-90 μM, respectively. The limits of detection of RDX and HMX are 96 and 110 nM, respectively. Importantly, this assay is employed for the detection of RDX and HMX in real water, proving the applicability of the assay in real-world samples.

References

Dec 17, 2009·Journal of Hazardous Materials·Mahmoud Tabrizchi, Vahideh Ilbeigi
Aug 10, 2013·Journal of the American Chemical Society·Longhua GuoDong-Hwan Kim
Mar 1, 2014·Chemical Society Reviews·Zhichao HuJing Li
Mar 26, 2014·Chemical Reviews·Ying ZhouJuyoung Yoon
Apr 3, 2014·Biosensors & Bioelectronics·Chunjing FengLei Wang
Jan 15, 2015·ACS Applied Materials & Interfaces·Dong Jin KangBumjoon J Kim
Jan 21, 2015·Journal of the American Chemical Society·Hengquan YangBernard P Binks
Feb 25, 2015·Analytical Chemistry·Ali K YetisenSeok Hyun Yun
Jun 16, 2015·Journal of the American Chemical Society·Lorenzo MoscaPavel Anzenbacher
Aug 21, 2015·Analytical Chemistry·Tianhuan PengDi Li
Nov 3, 2015·Journal of the American Chemical Society·Jianping HuangHengquan Yang
Jul 19, 2016·Journal of the American Chemical Society·Ming ZhangHengquan Yang
Jan 26, 2018·Physical Chemistry Chemical Physics : PCCP·Wei HuangYi He
Feb 20, 2018·Journal of the American Chemical Society·Xiaocun LuJeffrey S Moore

❮ Previous
Next ❯

Citations

Nov 6, 2018·Chemical Communications : Chem Comm·Nan XueHengquan Yang
Mar 15, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Haiquan LiuXin Liu
Oct 12, 2019·Small·Dae Seok KimDong Ki Yoon
Jan 2, 2021·Forensic Science International : Synergy·Douglas J KlapecJulie Pannuto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.