PMID: 9179351Jun 1, 1997Paper

Compatibility of parenteral nutrient solutions with selected drugs during simulated Y-site administration

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Lawrence A TrisselJ M Mirtallo

Abstract

The compatibility of 102 drugs with parenteral nutrient (PN) solutions during simulated Y-site administration was studied. Five milliliters of each of four representative PN solutions was combined in duplicate in a 1:1 ratio with 5-mL samples of solutions of 102 drugs in 5% dextrose injection or 0.9% sodium chloride injection. Visual examinations were performed in fluorescent laboratory light and under high-intensity monodirectional light, and turbidity was measured. Particle sizing and counting were performed for selected solutions. All evaluations were performed at intervals up to four hours; storage was at 23 degrees C. Most of the drugs tested were compatible with the PN solutions. However, 20 drugs exhibited various incompatibilities with one or more of the PN solutions. During simulated Y-site administration, four PN solutions were compatible with 82 of 102 drugs for four hours at 23 degrees C. Twenty drugs were incompatible with one or more of the PN solutions.

Citations

Feb 18, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Joseph I BoullataUNKNOWN American Society for Parenteral and Enteral Nutrition
Feb 18, 2020·European Journal of Hospital Pharmacy. Science and Practice·Vigdis StavenIngunn Tho
Jan 22, 2004·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Jay M Mirtallo
Nov 27, 2008·The Annals of Pharmacotherapy·Marko Puzovic, Gil Hardy
Jan 2, 2020·Pharmaceutics·Aleksandra GostyńskaAnna Jelińska
Mar 19, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·L A TrisselJ M Mirtallo
Apr 7, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Marko Puzovic, Gil Hardy
May 20, 2020·The Journal of Critical Care Medicine·Stijn VanstraelenAlaaddin Yilmaz
Nov 1, 2012·JPEN. Journal of Parenteral and Enteral Nutrition·Lucie BouchoudPascal Bonnabry
Apr 1, 2008·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Rachel SykesPeter Gal
Jan 1, 2007·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Christine A Robinson, Jaclyn E Lee
Jan 1, 2009·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Christine A Robinson, Jaclyn E Sawyer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Lawrence A TrisselD L Gilbert
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Lawrence A TrisselJ F Martinez
American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Lawrence A TrisselM C Kim
© 2021 Meta ULC. All rights reserved