Compensation: a contemporary regulatory machinery in cardiovascular diseases?

Cardiovascular Toxicology
Xiu-Juan Fan, Jun Ren

Abstract

Both clinical and experimental findings at the molecular, cellular, tissue, organ and systematic levels have depicted the presence of a contemporary regulatory machinery namely compensation in various forms of cardiovascular diseases. Compensation is believed to be present and regulated within the scope of a biological entity and represents the initiation of dyshomeostasis. Compensation can be identified in multiple categories and organs in cardiovascular diseases at multiple levels. The capacity to reduce the unfavorable pathological compensation may be a criterion to evaluate the therapeutic effectiveness for cardiovascular diseases. This mini-review tries to take compensation into consideration in the understanding of onset and progression of cardiovascular diseases in particular, and thus, better or optimal therapeutic approaches may be achieved for the prevention and management of cardiovascular diseases.

References

Jan 1, 1977·Annual Review of Biochemistry·J L Goldstein, M S Brown
Jun 4, 1992·The American Journal of Cardiology·G ManciaG Grassi
Nov 1, 1986·Circulation Research·K SchwartzM Buckingham
Sep 1, 1996·Journal of Cardiac Failure·Y SetaD L Mann
Dec 10, 1999·The American Journal of Cardiology·H Siragy
Apr 6, 2000·The American Journal of Cardiology·L H YoungA J Sinusas
Jun 12, 2002·Journal of Molecular and Cellular Cardiology·Sandrine LecourMichael N Sack
Aug 16, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Giandomenico NolloRenzo Antolini
Sep 14, 2002·The Journal of Biological Chemistry·Tilman Sánchez-ElsnerCarmelo Bernabéu
Dec 17, 2002·Experimental Physiology·Michael Harbuz
Jul 4, 2003·The New England Journal of Medicine·Elizabeth G Nabel
Mar 12, 2004·Journal of the American College of Cardiology·Aun Yeong ChongGregory Y H Lip
Nov 18, 2004·Proceedings of the National Academy of Sciences of the United States of America·M SethG Inesi
Mar 23, 2005·The Journal of Biological Chemistry·Carsten SkurkKenneth Walsh
Oct 14, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Tepmanas Bupha-IntrR J Solaro
Oct 31, 2006·International Journal of Cardiology·Mutsuko Nonaka-SarukawaKazuyuki Shimada
Nov 23, 2006·Cellular & Molecular Biology Letters·Pavan AtluriY Joseph Woo
Jan 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Michael I DorrellMartin Friedlander
Jan 16, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Yukiko AbeKoji Hasegawa
Feb 27, 2007·Nature Genetics·Ido AmitYosef Yarden
May 1, 2007·Diabetes Research and Clinical Practice·Seok Man Son
May 15, 2007·The Journal of Physiology·Patrick T FuegerDavid H Wasserman
Jun 15, 2007·Expert Opinion on Pharmacotherapy·Dawn Smiley, Guillermo Umpierrez
Jul 31, 2007·Trends in Cardiovascular Medicine·Morris KarmazynAsad Zeidan
Sep 4, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Elisabeth A Gustafson-WagnerJim J-C Lin
Sep 11, 2007·Journal of the American College of Cardiology·Anna SeverinoAlfonso Baldi
Jan 4, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Joseph A BlansfieldSteven K Libutti
Jan 22, 2008·Trends in Cardiovascular Medicine·Franck Lebrin, Christine L Mummery
Feb 20, 2008·Angiogenesis·Peter ten DijkeEvangelia Pardali
May 15, 2008·The Journal of Biological Chemistry·Meriem BourajjajLeon J De Windt
Jul 24, 2008·American Journal of Physiology. Endocrinology and Metabolism·Haruyo YamashitaIra J Goldberg
Sep 12, 2008·Proceedings of the National Academy of Sciences of the United States of America·John A MuraskiMark A Sussman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved