PMID: 6983204Sep 1, 1982Paper

Complement aberrations in serum from children with otitis due to S. pneumoniae or H. influenzae

Acta Oto-laryngologica
K Prellner, N I Nilsson

Abstract

Complement components C1q, C1s, C3, C4, factor B and properdin were measured, together with C1 subcomponent complexes and Cq binding substances in acute and convalescent samples from patients with relapsing and non-relapsing otitis media due to S. pneumoniae and H. influenzae. Analysis of C1 subcomponent complexes together with the finding of low C1q levels gave evidence of a disturbed C1 function in acute OME. Furthermore, complement activation by the classical and by the alternative pathways was demonstrated. Complement aberrations were more pronounced in relapsing otitis than in non-relapsing otitis. C1q binding substances that might possibly cause the complement aberrations found were present in most of the patients.

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Citations

Jan 1, 1988·Acta Oto-laryngologica. Supplementum·D J LimL O Bakaletz
Jan 1, 1989·Acta Oto-laryngologica. Supplementum·K Prellner, O Kalm
Jan 1, 1984·Acta Oto-laryngologica. Supplementum·C RosénM Walder
Jun 9, 1998·Annals of the New York Academy of Sciences·K Prellner, O Kalm
Mar 1, 1984·International Journal of Pediatric Otorhinolaryngology·K PrellnerF K Pedersen
Aug 1, 1990·The Annals of Otology, Rhinology, and Laryngology·K PrellnerJ Heldrup
Sep 1, 1986·International Journal of Pediatric Otorhinolaryngology·O KalmP Christensen
Mar 1, 1988·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·C H Sørensen, L K Nielsen
Dec 1, 1982·Clinical Genetics·M KjellmanA G Sjöholm
Dec 1, 1985·Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section C, Immunology·K PrellnerA G Sjöholm

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